Senior Research Associate (Animal Genetics)
Мэтч & Сопровод
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Описание вакансии
TL;DR
Senior Research Associate (Animal Genetics): Culturing and genetically modifying primordial germ cells for the generation of transgenic chickens with an accent on gene editing, germline transmission, and molecular characterization. Focus on developing innovative in vivo platforms for antibody discovery and maintaining high-quality cell lines for therapeutic research.
Location: Must be based in Emeryville, CA (Onsite)
Salary: $105,345–$128,086 per year
Company
provides pharmaceutical partners with diverse antibody repertoires and cutting-edge screening technologies to enable the discovery of next-generation therapeutics.
What you will do
- Propagate and genetically modify chicken primordial germ cells (PGCs) while monitoring growth characteristics.
- Design and implement precision gene editing tools for PGC modification.
- Produce germline chimeras via microinjection and evaluate germline competence in re-derived lines.
- Characterize PGC lines and transgenes using immunological methods, PCR, and sequencing.
- Evaluate novel antibody formats in immortalized B cells using flow cytometry and molecular techniques.
- Collaborate on immunophenotyping and genotyping tasks while maintaining accurate laboratory records.
Requirements
- M.S. degree with 5+ years of relevant experience.
- Must be able to work onsite in Emeryville, CA, Monday–Friday, 8am–5pm PT.
- Proven experience with stem cell culture and genetic modification.
- Strong background in molecular biology techniques.
- Ability to prioritize tasks and manage projects effectively in a team environment.
- Excellent communication and organizational skills.
Nice to have
- Experience with antibody discovery or characterization.
- Experience working with transgenic animals.
Culture & Benefits
- Comprehensive health plans and wellness stipend.
- Immediate 401k matching and equity/refresh grants.
- Paid parental leave, PTO, and sick leave.
- Commuter benefits and education reimbursement.
- Collaborative and innovative team environment focused on drug discovery.
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