Scientist Immunology

TL;DR

Scientist Immunology: Conceive, design, and execute in vitro and in vivo studies to uncover mechanisms of inflammatory and autoimmune diseases with an accent on immune cell biology, cell signaling, and immunological assay development. Focus on identifying and validating drug targets and biomarkers, generating translational research data, and collaborating cross-functionally to drive drug discovery and development.

Location: San Francisco, CA (based in South San Francisco, California; frequent onsite presence; commutable distance or able to self-relocate)

Salary: $111,000.00-$144,000.00

Company

hirify.global is a global biotechnology company developing life-changing medicines.

What you will do

• Conceive, design, and execute in vitro and in vivo studies to explore mechanisms underlying inflammatory and autoimmune diseases.
• Identify and validate new drug targets, biomarkers, and pathways relevant to immune-mediated disorders.
• Generate data supporting lead optimization, biomarker discovery, and translational research.
• Generate and interpret complex datasets and present findings internally and externally (meetings, conferences, publications).
• Collaborate cross-functionally with pharmacology, medicinal chemistry, protein engineering, and computational/translational sciences to drive target identification/validation and drug discovery.
• Stay abreast of scientific advances and emerging technologies in immunology and inflammation to foster scientific excellence and innovation.

Requirements

• Location/onsite: Based in South San Francisco, California with frequent onsite presence; must be within commutable distance or able to self-relocate.
• PhD, MS, or BS in Immunology, Cellular and Molecular Biology, or a related field (PhD preferred) with 0-2+ years of industry experience (MS 4+ years; BS 6+ years).
• Strong expertise in immune cell biology (innate and adaptive immunity), cell signaling, and immunological assay development.
• Hands-on experience with biochemical and cellular assay development, tissue culture, multiparametric flow cytometry (e.g., 15+ colors), ELISA/MSD, RNA & protein analysis (e.g., RNA-seq/qPCR, Jess), and CRISPR.
• Experience isolating and culturing primary murine and human cells or patient-derived samples.
• Ability to work independently and collaboratively in a fast-paced environment with strong problem-solving skills.

Nice to have

• Experience with disease models of inflammation and/or autoimmunity.
• Prior experience in biotech/pharma drug discovery or translational research.
• Experience with small-molecule and biologics drug discovery.
• Experience with multiomics analyses (genomic, transcriptomic, proteomics, etc.).

Culture & Benefits

• Medical, dental, vision, and life insurance.
• Fitness and wellness programs with fitness reimbursement.
• Short- and long-term disability insurance.
• Minimum 15 days paid vacation plus end-of-year shutdown time off (Dec 26–Dec 31), plus paid holidays and personal days.
• 401(k) with company-matched contributions, employee stock purchase plan, and tuition reimbursement up to $10,000 per calendar year.
• Employee Resource Groups participation; paid maternity and parental leave; 80 hours sick time per calendar year.

Hiring process

• Interviews to assess scientific background, drug discovery experience, and ability to work cross-functionally.
• Evaluation of technical fit through discussion of relevant experimental work and data interpretation.