Senior Automation Engineer I (Syncade MES)

TL;DR

Senior Automation Engineer I (Syncade MES): Managing and optimizing Syncade MES infrastructure within a GMP-regulated biopharmaceutical manufacturing environment with an accent on system administration, data integrity, and cross-functional technical support. Focus on leading root cause investigations, executing validation deliverables, and driving continuous improvement for manufacturing execution systems.

Location: Must be based in Research Triangle Park, NC

Salary: $93,000–$121,000

Company

A global biotechnology company dedicated to delivering life-changing medicines through innovation and a commitment to excellence.

What you will do

• Act as the primary system administrator and SME for Syncade MES, handling configuration, maintenance, and troubleshooting.
• Ensure system availability, performance, and data integrity to support GMP manufacturing operations.
• Lead root cause investigations and implement corrective/preventive actions for MES-related deviations.
• Manage user access, security roles, and audit trail reviews in compliance with GxP and cybersecurity standards.
• Execute change controls, including system updates, enhancements, and validation deliverables (IQ/OQ/PQ).
• Support integration and data flow between Syncade and other enterprise systems like DeltaV, PI, and LIMS.

Requirements

• Bachelor’s degree in Engineering required.
• 5–8+ years of automation engineering experience in a regulated environment.
• Minimum of 3 years of experience with Syncade/MES infrastructure, workflows, and eBR design.
• Strong understanding of GxP compliance, data integrity, and change control processes.
• Proven ability to independently troubleshoot and resolve complex technical issues.

Nice to have

• Experience with Emerson DeltaV (DCS) integration.
• Experience with AVEVA PI System for data collection and analytics.
• Familiarity with Infobatch for batch reporting.
• Participation in system upgrades or tech transfers.

Culture & Benefits

• Comprehensive medical, dental, vision, and life insurance plans.
• 401(k) program with company matching contributions.
• Minimum of 15 days of paid vacation plus end-of-year shutdown.
• Paid maternity and parental leave.
• Tuition reimbursement up to $10,000 per year.
• Fitness and wellness programs with reimbursement.