pharmacologyfacsbiochemistryassay automationcell based assayscell cultureqpcrwestern blot
Вакансия из Hirify Global, списка международных tech-компаний Для мэтча и отклика нужен Plus
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Hirify AI/Оригинал
TL;DR
Senior Biologist (Cell-Based Assays/Pharmacology): Developing and optimizing mammalian cell-based, biochemical, enzymatic, and screening assays for novel therapeutics with an accent on transfections, stable cell lines, pharmacological analysis, and automated 96-/384-well workflows. Focus on designing complex in vitro assays, analyzing gene expression and functional readouts, and evaluating drug potency, efficacy, and mechanisms of action.
Location: Boston, Massachusetts, United States; onsite laboratory role.
Salary: $155,600.
Company
hirify.global provides staffing and temporary assignment services for technical and scientific roles.
What you will do
Develop cell-based functional, biochemical, enzymatic, and screening assays for novel therapeutics.
Perform aseptic mammalian cell culture, transient transfections, and stable cell line generation.
Design, develop, and optimize in vitro enzymatic assays, including ADP-Glo and Kinase-Glo.
Operate plate readers, liquid-handling robots, and assay automation systems using 96- and 384-well formats.
Conduct gene expression studies using qPCR, western blot, and FACS.
Analyze concentration-response curves, binding affinity, potency, Hill slope, in vitro efficacy, and drug mechanisms of action.
Requirements
8–10 years of laboratory experience.
B.S. and/or M.S. in Biology, Pharmacology, Biochemistry, or a related field.
Expertise in mammalian cell culture, transfections, cell-based assays, biochemical and enzymatic assays, and therapeutic screening.
Knowledge of basic pharmacology and experience with colorimetric, luminescence, fluorescence, and HTRF readouts.
Strong communication, independent data analysis, accurate record keeping, prioritization, and attention to detail.
Ability to work onsite in Boston, United States.
Nice to have
Experience with native cell lines, primary cell cultures, iPSCs, co-cultures, or 3D cultures.
Industry experience and exposure to multiple therapeutic target classes and modalities.
Experience with ELISA assays.
Background in cardiometabolic diseases.
Culture & Benefits
Work independently and collaboratively across scientific projects.
Temporary assignments lasting 13 weeks or longer may include major medical, dental, vision, 401(k), and statutory sick pay where required.
Reasonable accommodations are available during the employment process.
hirify.global participates in E-Verify in certain locations as required by law.
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