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Biologist

155 600$
Формат работы
onsite
Тип работы
fulltime
Грейд
senior
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Senior Biologist (Cell-Based Assays/Pharmacology): Developing and optimizing mammalian cell-based, biochemical, enzymatic, and screening assays for novel therapeutics with an accent on transfections, stable cell lines, pharmacological analysis, and automated 96-/384-well workflows. Focus on designing complex in vitro assays, analyzing gene expression and functional readouts, and evaluating drug potency, efficacy, and mechanisms of action.

Location: Boston, Massachusetts, United States; onsite laboratory role.

Salary: $155,600.

Company

hirify.global provides staffing and temporary assignment services for technical and scientific roles.

What you will do

  • Develop cell-based functional, biochemical, enzymatic, and screening assays for novel therapeutics.
  • Perform aseptic mammalian cell culture, transient transfections, and stable cell line generation.
  • Design, develop, and optimize in vitro enzymatic assays, including ADP-Glo and Kinase-Glo.
  • Operate plate readers, liquid-handling robots, and assay automation systems using 96- and 384-well formats.
  • Conduct gene expression studies using qPCR, western blot, and FACS.
  • Analyze concentration-response curves, binding affinity, potency, Hill slope, in vitro efficacy, and drug mechanisms of action.

Requirements

  • 8–10 years of laboratory experience.
  • B.S. and/or M.S. in Biology, Pharmacology, Biochemistry, or a related field.
  • Expertise in mammalian cell culture, transfections, cell-based assays, biochemical and enzymatic assays, and therapeutic screening.
  • Knowledge of basic pharmacology and experience with colorimetric, luminescence, fluorescence, and HTRF readouts.
  • Strong communication, independent data analysis, accurate record keeping, prioritization, and attention to detail.
  • Ability to work onsite in Boston, United States.

Nice to have

  • Experience with native cell lines, primary cell cultures, iPSCs, co-cultures, or 3D cultures.
  • Industry experience and exposure to multiple therapeutic target classes and modalities.
  • Experience with ELISA assays.
  • Background in cardiometabolic diseases.

Culture & Benefits

  • Work independently and collaboratively across scientific projects.
  • Temporary assignments lasting 13 weeks or longer may include major medical, dental, vision, 401(k), and statutory sick pay where required.
  • Reasonable accommodations are available during the employment process.
  • hirify.global participates in E-Verify in certain locations as required by law.

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