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6 дней назад

Scientist – Disease Biology Discovery Research (Cardiometabolic Disorders)

123 053 - 166 483$
Формат работы
onsite
Тип работы
fulltime
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Scientist – Disease Biology Discovery Research (Cardiometabolic Disorders): Developing a deep understanding of disease biology and validating novel therapeutic targets for cardiac, cardiovascular, fibrotic, and renal diseases with an accent on molecular and cell biology, in vitro and ex vivo mechanism-of-action experiments, and preclinical research. Focus on designing complex cellular assays, analyzing biological datasets, and advancing drug development programs through collaborative scientific contributions.

Location: On-site in South San Francisco, California, United States

Annual salary: $123,052.80–$166,483.20 USD

Company

hirify.global is a biotechnology company developing and delivering medicines for serious illnesses across cardiovascular, rare, inflammatory, metabolic, and other disease areas.

What you will do

  • Develop a deep understanding of disease biology and identify novel drug targets in non-oncology indications.
  • Generate robust data for preclinical validation of therapeutic targets and advance the understanding of disease mechanisms.
  • Design and execute in vitro and ex vivo mechanism-of-action experiments, including assay optimization and troubleshooting.
  • Collect, analyze, and interpret experimental data and complex datasets.
  • Present research findings in written and oral formats to internal teams and external collaborators.
  • Contribute as a scientific and technical expert to cross-functional drug development teams.

Requirements

  • PhD, or a master’s degree with 2 years of molecular and cell biology experience, or a bachelor’s degree with 4 years of molecular and cell biology experience.
  • Experience with cell-based, molecular, and biochemical techniques, including RNA isolation, qPCR, protein immunoprecipitation, immunoblotting, ELISA, flow cytometry, and cell imaging.
  • Experience conducting in vitro and cellular assays to study gene function or therapeutic molecule mechanisms of action.
  • Strong data analysis, scientific communication, interpersonal, organizational, and record-keeping skills.
  • Ability to work on-site in South San Francisco, California.

Nice to have

  • Experience with cell line engineering, including CRISPR and virus-based stable cell line generation.
  • Expertise with human iPSCs, particularly iPSC-derived cardiomyocytes.
  • High-impact publications demonstrating relevant assay and disease biology experience.

Culture & Benefits

  • Collaborative, innovative, and science-based working environment.
  • Permanent position with opportunities for career development and advancement.
  • Health, dental, vision, life, disability, and flexible spending benefits.
  • Retirement and savings plan with company contributions.
  • Annual bonus program, stock-based long-term incentives, and paid time off.

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