Senior Principal Scientist (Psychiatry)

TL;DR

Senior Principal Scientist (Psychiatry): Planning and overseeing scientific strategy for psychiatry-focused clinical trial services across studies with an accent on rater training, central monitoring, and endpoint data quality. Focus on designing training programs for scales like MADRS and HAM-D, analyzing data quality signals such as rater drift, and ensuring reliable clinical outcomes.

Location: Remote within the United States, Australia, or the United Kingdom

Salary: $165,000–$180,000 USD

Company

Advancing brain health through validated digital cognitive assessments used in over 2,000 clinical trials across 150+ countries.

What you will do

• Oversee scientific delivery of psychiatry services including rater training and central monitoring across study portfolios.
• Define study-specific plans for endpoint quality, integrating central monitoring workflows.
• Provide scientific leadership on scale selection, administration, and feasibility for internal teams and sponsors.
• Design and implement rater training programs with certification and remediation.
• Monitor data quality signals, rater drift, and deviations, guiding follow-up actions.
• Collaborate on SOPs, staff development, product refinement, and business development proposals.

Requirements

• Post-graduate degree in psychology, psychiatry, neuroscience, or related field.
• Scientific track record in publications, presentations, patents, or grants.
• 6+ years neuropsychological experience; 5+ years in clinical trials, preferably CNS/psychiatry.
• Expertise in psychiatric scales (MADRS, PANSS, HAM-D, YMRS) and structured interviews (SIGMA).
• Experience with rater training, central monitoring, or data quality oversight.
• Managing scientific projects, directing staff, and interacting with clinical professionals.

Nice to have

• Understanding of cognition measurement tools, including computer-based assessments.

Culture & Benefits

• Virtual-first remote work within US, Australia, or UK.
• 20 days vacation, 10 personal days, 10 paid holidays.
• 401(k) matching up to 3%, comprehensive health/dental/vision, disability/life insurance.
• Pre-tax FSA accounts, learning/development opportunities including mentorships and certifications.