Global Commercial Strategy (GCS): Senior Manager, Early GI, Rheumatology, and Neurology (Pharmaceutical Strategy)

Location: Hybrid in New York City, New York, or Cambridge, Massachusetts, United States. Candidates must have permanent authorization to work in the United States. U.S. work visa sponsorship is not available.

Annual base salary: $124,400–$207,400, plus eligibility for a 17.5% bonus target and share-based long-term incentive program.

Company

hirify.global develops medicines and operates a Global Commercial Strategy organization that translates R&D science into patient, portfolio, and commercial value across the asset lifecycle.

What you will do

• Develop long-range commercial and portfolio strategies across early pipeline assets, lifecycle opportunities, external innovation, and emerging opportunities in rheumatology, GI, and neurology.
• Synthesize scientific, clinical, commercial, access, competitive, and patient insights into portfolio recommendations, investment priorities, and strategic trade-offs.
• Lead early commercial assessments, product concepts, target product profiles, positioning hypotheses, market archetypes, opportunity assessments, and forecast assumptions.
• Provide commercial strategy input for business development and external innovation opportunities, including strategic fit, market potential, valuation inputs, and portfolio implications.
• Prepare executive-ready materials and influence cross-functional governance decisions with R&D, Medical Affairs, GASP, BAI, Competitive Intelligence, Business Development, and commercial teams.
• Embed responsible AI-enabled tools and repeatable workflows into landscape synthesis, scenario development, portfolio reviews, and decision support.

Requirements

• Bachelor’s degree required; MBA or another advanced degree is preferred.
• At least 6 years of relevant experience with a BA/BS, 5 years with an MBA/MS, or 1 year with a PhD or JD in pharmaceuticals, biotechnology, life sciences, commercial development, portfolio strategy, corporate strategy, business development, market research, forecasting, analytics, or a related field.
• Strong strategic and analytical skills, including the ability to synthesize complex scientific, clinical, market, access, and competitive information into clear recommendations.
• Experience leading early commercial assessments, business cases, opportunity assessments, or cross-functional strategic planning.
• Ability to engage in scientific and clinical dialogue and translate implications into commercial opportunity, differentiation, portfolio value, and enterprise decisions.
• Strong communication, executive presence, problem-solving, stakeholder management, collaboration, and influencing skills.
• Ability to develop and coach others and guide colleagues’ work toward meaningful outcomes and business impact.

Nice to have

• Advanced degree in business, life sciences, public health, medicine, pharmacy, or a related field.
• Experience in rheumatology, GI, neurology, I&I, specialty care, or other complex therapeutic areas.
• Experience with commercial development, early asset strategy, portfolio management, business development assessments, forecasting, valuation, or investment prioritization.
• Experience developing long-term product or disease-area strategies and securing senior leadership alignment.
• Understanding of market access, payer considerations, evidence generation, value demonstration, and lifecycle value optimization.
• Experience leading cross-functional teams, influencing without authority, and making recommendations with incomplete information.
• Experience using AI tools for strategy, synthesis, or analysis; comfort working in an AI-native or AI-augmented environment.
• Ability to operate in ambiguity, maintain an enterprise mindset, adapt to changing portfolio priorities, and handle confidential matters with discretion.

Culture & Benefits

• Hybrid work location with comprehensive benefits, including 401(k) matching and an additional retirement savings contribution.
• Paid vacation, holidays, personal days, caregiver/parental leave, medical leave, and medical, prescription, dental, and vision coverage.
• Eligibility for hirify.global’s Global Performance Plan with a 17.5% bonus target and a share-based long-term incentive program.
• Work emphasizes science, technology, transformation, collaboration, enterprise thinking, accountability, and talent development.
• Permanent U.S. work authorization is required; visa sponsorship is unavailable now and in the future.

Hiring process

• Applications are accepted until November 12, 2026.
• Local pay information may be provided during the first interview for secondary posting locations subject to pay-transparency regulations.