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4 дня назад

Research Associate (Mass Spectrometry Proteomics)

37 694GBP
Формат работы
hybrid
Тип работы
fulltime
Английский
b2
Страна
UK
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Research Associate (Mass Spectrometry Proteomics): Investigating how collagen glycosylation affects cartilage health in osteoarthritis by combining cell biology, CRISPR-Cas9, primary cell culture, western blotting, and LC-MS/MS proteomics with an accent on chondrocyte and extracellular matrix analysis. Focus on independently designing rigorous experiments, performing mass spectrometry-based proteomic studies, collaborating across laboratories, and publishing findings.

Location: Manchester, Greater Manchester, United Kingdom; laboratory-based role at Oxford Road. Hybrid working arrangements may be considered.

Salary: £37,694 per annum.

Company

The hirify.global's Rice Lab is part of the Division of Musculoskeletal and Dermatological Sciences and collaborates with the proteomics laboratory of Professor Matthias Trost.

What you will do

  • Investigate the effect of collagen glycosylation on cartilage health in the context of osteoarthritis.
  • Perform molecular and cell biological experiments, including CRISPR-Cas9, primary cell culture, and western blotting.
  • Use downstream LC-MS/MS to characterise chondrocyte and extracellular matrix proteomes.
  • Independently perform experiments and work with the Principal Investigator to conceptualise studies and design experiments.
  • Publish findings in appropriate journals and contribute to a collaborative team-science approach.
  • Support team members and trainees intellectually and practically while working with internal and external collaborators.

Requirements

  • Postdoctoral experience as a mass spectrometrist or proteomics expert.
  • Substantial hands-on experience with mass spectrometry platforms.
  • Demonstrable knowledge of cell biology relevant to the laboratory's research focus.
  • Experience with cell biology activities, including primary cell culture and western blotting.
  • Experience or capability in using CRISPR-Cas9 and LC-MS/MS proteomics.
  • Ability to perform experiments independently, conceptualise studies, and design rigorous experiments.
  • Ability to collaborate with internal and external research partners and support colleagues and trainees.

Culture & Benefits

  • Collaborative team-science environment involving the Rice Lab and the hirify.global proteomics laboratory.
  • Market-leading pension scheme.
  • Employee health and wellbeing services, including an Employee Assistance Programme.
  • Generous annual leave entitlement, bank holidays, and additional paid closure over Christmas.
  • Local and national discounts at major retailers.
  • Flexible working and possible hybrid working arrangements.

Hiring process

  • Interviews will take place on 23 and 24 February.
  • The vacancy closes at midnight on the stated closing date.

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