Bioinformatician – Structural Proteomics & Integrative Modelling (Structural Proteomics)

Location: Hinxton, Cambridgeshire, United Kingdom; flexible working arrangements include hybrid working patterns.

Salary: £3,452 or £3,861 per month after tax, depending on grade, plus benefits and financial allowances. The contract is fixed-term for 3 years and grant-funded.

Company

hirify.global-EBI is a research organisation that develops and maintains open biological databases, tools and infrastructure for the global scientific community.

What you will do

• Analyse XL-MS, CF-MS, AP-MS and integrative modelling workflows to define data and metadata requirements.
• Develop standards, data models and interoperable tools connecting proteomics and structural biology formats.
• Build tools, APIs, workflows and documentation for compliant data deposition, conversion and local validation.
• Implement cross-modality validation, identifier mapping and provenance tracking between experimental evidence, structural restraints and integrative models.
• Establish linked deposition, release, search, visualisation and programmatic access services with PRIDE and PDB-IHM colleagues.
• Engage with researchers, standards communities and analysis-tool developers, and contribute to publications, training and dissemination.

Requirements

• PhD in bioinformatics, computational biology, structural biology, proteomics, computer science or a related field.
• Knowledge of structural biology, protein structures, molecular interaction data and protein sequence, structure and functional annotations.
• Experience with biological data, metadata, identifiers, scientific repositories and data-integration workflows.
• Scientific software development experience, preferably with Python, plus experience with APIs or data-processing pipelines.
• Experience with Linux, Git, testing, documentation, FAIR data principles, metadata standards and reproducible research.
• Relevant scientific publications and strong communication, collaboration and problem-solving skills.

Nice to have

• Experience with integrative or hybrid modelling, structure prediction, macromolecular modelling or mass-spectrometry-based proteomics.
• Familiarity with IHMCIF, mmCIF, mzIdentML or SDRF-Proteomics standards.
• Experience developing validators, conversion tools, deposition systems, scientific web services, REST APIs, databases, containers or workflow-management systems.
• Experience with data visualisation, analysis, international interdisciplinary collaboration or AI-assisted coding with appropriate testing and validation.

Culture & Benefits

• Collaborative and inclusive international research environment on the Wellcome Genome Campus.
• Hybrid working arrangements, 30 days of annual leave and public holidays.
• Private medical insurance, pension and insurance schemes, family and child allowances, and parental benefits.
• Relocation package with an installation grant where required.
• International applicants may be offered visa exemptions, with additional support for eligible non-UK residents.
• Campus facilities include a shuttle bus, library, gym, cafeteria, nursery and sports and social clubs.

Hiring process

• Submit a CV and cover letter through the online application system.
• Initial interviews are expected to take place via Zoom in November 2026.
• Applications close at 23:59 CET on 03 November 2026.