Cell Assay Senior Scientist - Blue Sky Kinases

Location: Memphis, Tennessee, United States; onsite research role

Salary: $104,000–$186,160 per year

Company

hirify.global conducts interdisciplinary biomedical research focused on understanding disease and developing new therapeutic opportunities.

What you will do

• Research kinase-mediated signaling pathways, kinase targets, phosphorylation events, and cellular outcomes.
• Identify appropriate cells and assays for structure-guided analysis of kinase signaling and cellular phenotypes.
• Develop and implement assays covering phosphorylation, protein interactions, localization, RNA and protein abundance, and ubiquitination.
• Develop phenotypic assays for viability, apoptosis, autophagy, migration, differentiation, and related cellular outcomes.
• Optimize and troubleshoot cell-based assays across high-, medium-, and low-throughput platforms.
• Perform statistical analysis, interpret results, and communicate findings with the Cell-Based Assays team and project collaborators.

Requirements

• Bachelor's degree in a relevant scientific area is required.
• Five years of relevant experience with a PhD, eight years with a Master's degree, or ten years with a Bachelor's degree.
• Experience analyzing protein kinases and phosphorylation-dependent signaling pathways.
• Expertise culturing diverse cell types, including cancer cell lines, primary cells, immune cells, neuronal cells, and muscle cells.
• Experience with exogenous protein expression, cloning, PCR, qRT-PCR, transfection, transduction, infection, immunoassays, immunoprecipitation, and Western blotting.
• Experience with flow cytometry/FACS, reporter gene assays, phenotypic assays, microscopy, cellular fractionation, or protein-protein interaction analysis.

Nice to have

• Experience with mouse models.
• Experience using graphing software or R scripts for statistical analysis.

Culture & Benefits

• Access to world-class facilities and state-of-the-art technologies.
• Collaborative, interdisciplinary, bench-to-bedside research environment.
• Opportunities for learning, professional growth, and career development.
• Generous paid time off, work-life balance, and on-campus conveniences.