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13 дней назад

Cell Assay Lead/Principal Scientist - Blue Sky Kinases

138 320 - 262 080$
Формат работы
onsite
Тип работы
fulltime
Грейд
senior/lead
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Cell Assay Lead/Principal Scientist - Blue Sky Kinases (Cell Biology/Protein Kinases): Designing and executing cell-based assays to translate structural insights into functional effects in cells with an accent on kinase signaling, phosphorylation events, and cellular phenotypes. Focus on optimizing complex assays across diverse cell types, analyzing experimental data, and guiding junior scientists on structure-guided kinase projects.

Location: Memphis, Tennessee, United States

Salary: $138,320–$262,080 per year

Company

hirify.global conducts interdisciplinary biomedical research focused on understanding disease mechanisms and developing therapeutic opportunities.

What you will do

  • Research kinase-mediated signaling pathways, kinase targets, phosphorylation events, and cellular outcomes.
  • Design and implement cell-based assays across cancer cell lines, primary cells, immune cells, neuronal cells, muscle cells, and other models.
  • Translate structural biology findings into functional studies of kinase regulation, signaling, and cellular phenotypes.
  • Lead multiple structure-guided cell biology projects and collaborate with cell-based assay and structural biology researchers.
  • Review literature and experimental data, troubleshoot assays, and perform statistical analysis using graphing software or R scripts.
  • Prepare research reports, communicate results, and mentor junior staff.

Requirements

  • Bachelor's degree in a relevant scientific area is required; PhD is preferred.
  • Ten years of relevant experience with a PhD, thirteen years with a Master's degree, or fifteen years with a Bachelor's degree.
  • Experience analyzing protein kinases and phosphorylation-dependent signaling pathways.
  • Expertise in cell culture and multiple methods of exogenous protein expression.
  • Experience with cloning, PCR, qRT-PCR, sterile technique, transfection, transduction, or infection.
  • Experience with immunoassays, Western blotting, protein interaction analysis, flow cytometry, reporter assays, phenotypic assays, microscopy, and cellular fractionation.

Nice to have

  • Experience with mouse models.

Culture & Benefits

  • World-class facilities and state-of-the-art technologies.
  • Collaborative, bench-to-bedside research environment.
  • Learning and career growth opportunities.
  • Generous paid time off and work-life balance support.
  • On-campus conveniences and institutional stability.

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