4 дня назад
Scientist (Cell & Tissue Operations)
125 000 - 140 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Scientist (Cell & Tissue Operations) (Cell Biology/Immunology): Processing human tissue, maintaining cell banks, and running immunological assays for human-first drug discovery with an accent on primary human cell culture, cryopreservation, flow cytometry, and rigorous documentation. Focus on executing partner studies, building reproducible SOPs, managing donor and cell-bank data, and strengthening GLP-like laboratory operations.
Location: Brisbane, CA, USA; fully onsite, with occasional weekend work for tissue arrivals and culture maintenance.
Salary: $125,000–$140,000 USD base salary per year, plus equity.
Company
is building a human-first drug discovery platform using organoids, AI, and real human biological data to improve translation from preclinical research to clinical outcomes.
What you will do
- Process human lymphoid tissue and primary cells into single-cell suspensions and organoid cultures.
- Apply donor acceptance criteria, track donor metadata, and optimize protocols under aseptic conditions.
- Perform cryopreservation, thawing, recovery, and cell banking with full chain of custody and LN2 inventory reconciliation.
- Run flow cytometry, ELISA, MSD, ELISpot, cytotoxicity, imaging, and qPCR assays as required.
- Analyze data using FlowJo, Prism, or equivalent tools and communicate findings in partner study summaries.
- Draft and revise SOPs, train team members, maintain equipment and reagent inventories, and support EH&S programs.
Requirements
- PhD in immunology, cell biology, bioengineering, or a related field with 0–2 years of postdoctoral or industry experience; or an MS with 5+ years of relevant industry experience; or a BS with 8+ years of relevant industry experience.
- Hands-on proficiency in primary human cell or tissue culture, strict aseptic technique, cryopreservation, and cell-stock tracking.
- Hands-on proficiency in flow cytometry and at least one additional immune assay method.
- Strong documentation, data integrity, scientific rigor, experimental design, communication, and data presentation skills.
- Ability to work fully onsite in Brisbane, California, including occasional weekend work.
- Ability to work with human-derived tissue and cells at BSL-2, wear a tight-fitting respirator when required, stand for extended periods, and lift up to 25 lb.
Nice to have
- Secondary lymphoid organ biology, organoid, or 3D culture experience.
- Formal cell banking with sterility, mycoplasma, and identity release testing.
- Spectral or high-parameter flow cytometry, including 15+ colors.
- iPSC culture, stem cell-derived immune models, higher-throughput workflows, or liquid-handling automation.
- SOP authoring in a GLP- or GMP-aware environment.
Culture & Benefits
- Human-relevant immunology work supporting drug development decisions.
- Early-team opportunity to build processes used as the company scales.
- Direct work on studies for biopharma partners.
- Growth path toward Scientist II and process leadership.
- Medical, dental, and vision coverage; 401(k); paid time off; equity.
- Hepatitis B vaccination is offered for work involving human-derived tissue and cells.
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