4 дня назад
Scientist, Analytical Development (mRNA)
109 200 - 174 600$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Scientist, Analytical Development (mRNA) (Separation Science/LC-MS): Developing and implementing separation-based analytical methods for clinical- and early-stage mRNA vaccines, therapeutics, and emerging modalities with an accent on LC/UHPLC, LC-MS, capillary electrophoresis, and product quality characterization. Focus on optimizing robust methods, troubleshooting complex analytical challenges, establishing platform approaches, and supporting qualification, validation, and technical transfer.
Location: Norwood, Massachusetts, United States; 100% onsite
Salary: $109,200–$174,600 per year, with potential bonus, incentive compensation, or equity eligibility.
Company
develops mRNA technology platforms, vaccines, therapeutics, and other advanced medicines.
What you will do
- Design, develop, optimize, and execute separation-based analytical methods for early- and clinical-stage products.
- Characterize product quality attributes, impurities, degradation products, identity, and purity using LC/HPLC/UHPLC, LC-MS, capillary electrophoresis, CE-SDS, and related technologies.
- Optimize chromatographic and electrophoretic parameters, sample preparation, detection, data processing, and system-suitability controls.
- Apply risk-based development, structured experimentation, and Design of Experiments to assess robustness and variability.
- Troubleshoot complex analytical results and integrate chromatographic, electrophoretic, mass-spectrometric, and orthogonal data.
- Support platform implementation, method pre-qualification, technical transfer, qualification, validation, documentation, and downstream Quality Control implementation.
Requirements
- Must work 100% onsite in Norwood, Massachusetts, United States.
- Only U.S. persons are eligible because the role involves access to export-controlled information; non-U.S. persons cannot be sponsored for an export control license.
- Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related field with 0–2 years of relevant experience; or M.S. with 8+ years; or B.S./B.A. with 10+ years of relevant industry experience.
- Strong hands-on experience with liquid chromatography and at least one additional separation platform, such as LC-MS or capillary electrophoresis.
- Knowledge of separation science, chromatographic and electrophoretic principles, method robustness, analytical controls, and data interpretation.
- Ability to independently plan experiments, troubleshoot technical issues, communicate scientific conclusions, and collaborate across multidisciplinary teams.
Nice to have
- Experience with mRNA, nucleic acids, lipid nanoparticles, proteins, vaccines, biologics, conjugates, or other advanced therapeutic modalities.
- Experience with CE-SDS, LC-MS, hyphenated analytical technologies, platform methods, or standardized approaches across multiple products.
- Familiarity with ICH Q14/Q2, analytical target profiles, method lifecycle principles, Empower, Chromeleon, laboratory automation, or automated data processing.
Culture & Benefits
- In-person work model with direct collaboration, mentorship, and hands-on site-based operations.
- Healthcare and voluntary benefit programs.
- Fitness, mindfulness, mental health, family planning, fertility, adoption, and surrogacy support.
- Paid vacation, volunteer days, sabbatical, global recharge days, and discretionary year-end shutdown.
- Savings and investment programs, plus location-specific benefits.
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