7 дней назад
Lead Researcher - In Vivo & In Vitro Screening
60 320 - 105 040$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Lead Researcher - In Vivo & In Vitro Screening (pediatric cancer research and drug screening): Leading in vitro and in vivo drug screening studies for leukemia and medulloblastoma with an accent on dose-response, combination therapy, synergism, and genomic analysis. Focus on developing molecular and cell-based assays, investigating therapeutic response mechanisms through short- and long-read RNA sequencing, and advancing candidates toward in vivo validation.
Location: Memphis, TN, United States
Salary: $60,320–$105,040 per year
Company
conducts translational research focused on developing improved therapies for children with cancer.
What you will do
- Lead and perform in vitro and in vivo drug screening studies using primary and patient-derived leukemia and medulloblastoma models.
- Design and execute dose-response, viability, combination therapy, and drug-synergy studies.
- Develop, optimize, and troubleshoot cell-based and molecular assays.
- Use short- and long-read RNA sequencing and other genomics approaches to investigate mechanisms of therapeutic response.
- Analyze experimental data, prioritize candidates, and advance studies toward in vivo validation.
- Design or coordinate in vivo efficacy studies and maintain comprehensive experimental records.
Requirements
- Bachelor’s degree in a relevant scientific area.
- At least 5 years of research experience, or at least 3 years with a master’s degree; no prior experience is required with a PhD.
- Strong knowledge of the principles underlying laboratory techniques and their application.
- Hands-on experience with molecular and cell biology, including cell culture, flow cytometry, DNA/RNA isolation, western blotting, and functional assays.
- Experience in laboratory R&D methods, research project execution, and comparable-role performance.
Nice to have
- Experience with drug screening, genomics, cancer models, or in vivo studies.
- Experience with established primary or patient-derived leukemia and medulloblastoma models.
Culture & Benefits
- Collaborative and interdisciplinary laboratory environment.
- Opportunity to build research productivity and contribute to high-position authorships on publications.
- Work focused on discovering new biology in high-risk leukemia research and developing improved pediatric cancer therapies.
- Benefits are provided as part of the employment package.
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