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7 дней назад

Lead Researcher - In Vivo & In Vitro Screening

60 320 - 105 040$
Формат работы
onsite
Тип работы
fulltime
Грейд
lead
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

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TL;DR
Lead Researcher - In Vivo & In Vitro Screening (pediatric cancer research and drug screening): Leading in vitro and in vivo drug screening studies for leukemia and medulloblastoma with an accent on dose-response, combination therapy, synergism, and genomic analysis. Focus on developing molecular and cell-based assays, investigating therapeutic response mechanisms through short- and long-read RNA sequencing, and advancing candidates toward in vivo validation.

Location: Memphis, TN, United States

Salary: $60,320–$105,040 per year

Company

hirify.global conducts translational research focused on developing improved therapies for children with cancer.

What you will do

  • Lead and perform in vitro and in vivo drug screening studies using primary and patient-derived leukemia and medulloblastoma models.
  • Design and execute dose-response, viability, combination therapy, and drug-synergy studies.
  • Develop, optimize, and troubleshoot cell-based and molecular assays.
  • Use short- and long-read RNA sequencing and other genomics approaches to investigate mechanisms of therapeutic response.
  • Analyze experimental data, prioritize candidates, and advance studies toward in vivo validation.
  • Design or coordinate in vivo efficacy studies and maintain comprehensive experimental records.

Requirements

  • Bachelor’s degree in a relevant scientific area.
  • At least 5 years of research experience, or at least 3 years with a master’s degree; no prior experience is required with a PhD.
  • Strong knowledge of the principles underlying laboratory techniques and their application.
  • Hands-on experience with molecular and cell biology, including cell culture, flow cytometry, DNA/RNA isolation, western blotting, and functional assays.
  • Experience in laboratory R&D methods, research project execution, and comparable-role performance.

Nice to have

  • Experience with drug screening, genomics, cancer models, or in vivo studies.
  • Experience with established primary or patient-derived leukemia and medulloblastoma models.

Culture & Benefits

  • Collaborative and interdisciplinary laboratory environment.
  • Opportunity to build research productivity and contribute to high-position authorships on publications.
  • Work focused on discovering new biology in high-risk leukemia research and developing improved pediatric cancer therapies.
  • Benefits are provided as part of the employment package.

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