Scientist R&D (Immunohistochemistry & Histology)

Location: Remote USA; the role is associated with San Carlos, California.

Salary: $125,000–$140,000 USD per year

Company

hirify.global develops cell-free DNA testing and personalized genetic diagnostics for oncology, women’s health, and organ health.

What you will do

• Design and execute development, optimization, verification, and validation studies for IHC, histology, and tissue-based workflows.
• Develop and optimize IHC assays, including antibody selection and titration, antigen retrieval, staining conditions, controls, and performance assessment.
• Optimize tissue fixation, FFPE processing, embedding, sectioning, H&E staining, microscopy, and slide preparation.
• Develop and troubleshoot automated IHC/ISH workflows, investigating staining artifacts, reagent performance, tissue quality, and assay variability.
• Plan moderate- to high-complexity experiments, analyze results using Excel, JMP, and image-analysis approaches, and communicate findings and recommendations.
• Collaborate with Pathology, Clinical Laboratory Operations, Quality, Automation, and other teams to transfer methods into clinical laboratory workflows and prepare protocols, reports, SOPs, and transfer documentation.

Requirements

• Ph.D. in Pathology, Cancer Biology, Molecular Biology, Cell Biology, Biomedical Sciences, or a related field with at least 2 years of relevant industry experience; or a Master’s degree with at least 5 years; or a Bachelor’s degree with 6–8+ years.
• Strong hands-on experience in IHC assay development, optimization, troubleshooting, antibody characterization, antigen retrieval, staining optimization, controls, tissue morphology, and assay performance evaluation.
• Solid knowledge of histology and FFPE tissue workflows.
• Ability to independently design and execute experiments, interpret data, troubleshoot technical challenges, and determine next steps.
• Strong technical writing, communication, collaboration, and organizational skills.

Nice to have

• Experience with automated IHC/ISH platforms, especially the Roche BenchMark ULTRA IHC/ISH System.
• Experience with H&E staining, microtomy, tissue sectioning, microscopy, digital pathology, or image analysis.
• Experience with NGS and molecular biology workflows, including FFPE nucleic acid extraction, PCR/qPCR, library preparation, or hybrid capture.
• Experience in regulated clinical laboratories, molecular diagnostics, or LDT environments.

Culture & Benefits

• Cross-functional collaboration across scientific, laboratory, quality, automation, and clinical operations teams.
• Medical, dental, vision, life, and disability plans for eligible employees and dependents.
• Free testing for employees and immediate family members, plus fertility care benefits.
• Pregnancy and baby bonding leave, 401(k) benefits, commuter benefits, and an employee referral program.