1 час назад
Associate Scientist II, MSAT (RNA/LNP)
81 000 - 89 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Associate Scientist II, MSAT (RNA/LNP): Supporting and improving preclinical and clinical-stage RNA and lipid nanoparticle manufacturing processes with an accent on process development, analytical testing, technology transfer, and scale-up. Focus on troubleshooting enzymatic reactions, chromatographic purification, TFF, filtration methods, and manufacturing robustness.
Location: Boston, Massachusetts, United States
Salary: $81,000–$89,000 annually, plus bonus and equity incentives
Company
is a clinical-stage biotechnology company developing programmable mRNA therapeutics for oncology and autoimmune disease using its Signal Stack platform.
What you will do
- Support the execution, continuous improvement, and maturation of preclinical and clinical-stage manufacturing processes.
- Perform lab-scale RNA and lipid nanoparticle production and analytical testing.
- Evaluate process improvements, troubleshoot technology transfer and manufacturing challenges, and support process scale-up.
- Author technical protocols and reports documenting experimental procedures, results, and conclusions.
- Collaborate with Process Development, Analytical Development, Automation, Quality, and external technical teams.
Requirements
- B.S. or advanced degree in Biochemistry, Chemical Engineering, or a related field.
- At least 2 years of biotech experience with RNA and/or lipid nanoparticle process improvement, manufacturing, or optimization.
- Experience with process development, scale-up, technology transfer, manufacturing support, and process troubleshooting.
- Experience optimizing enzymatic reactions, chromatographic purification, tangential flow filtration, and other filtration methods for biologics.
- Experience collecting, analyzing, and interpreting experimental data and communicating technical conclusions to cross-functional groups.
- Hands-on experience with RNA or lipid nanoparticle production and analytical methods such as UV-Vis spectroscopy, gel electrophoresis, ELISA, DLS, and RiboGreen.
Nice to have
- Experience with process characterization or later-stage development activities.
- Familiarity with ÄKTA systems and UNICORN control software.
Culture & Benefits
- Fast-paced, entrepreneurial, team-focused environment in a small biotechnology company.
- Health, dental, and life insurance benefits.
- Open paid time off and work-life flexibility.
- Onsite lunch catering and commuter support.
- Professional development within a collaborative team.
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