2 дня назад
Technician, Purification (Biotech)
70 500 - 78 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Technician, Purification (Biotech) (HPLC/LC-MS): Purifying and characterizing small-molecule compounds for synthetic chemistry programs using chromatographic and mass spectrometry techniques with an accent on high-throughput analysis, preparative purification, and analytical data integrity. Focus on operating open-access purification workflows, troubleshooting laboratory instrumentation, and delivering high-purity compounds with rapid turnaround.
Location: Monrovia, California, United States; laboratory-based onsite role. The initial training period follows a Monday–Friday, 9:00 AM–5:00 PM schedule. The permanent schedule is a four-day, 10-hour schedule: Saturday–Wednesday or Wednesday–Saturday.
Salary: $70,500–$78,000 annually, depending on experience.
Company
is a venture-backed biotechnology company combining nanotechnology, experimental science, machine learning, and automation to discover small-molecule medicines.
What you will do
- Develop and optimize analytical and preparative purification methods using reversed-phase and normal-phase HPLC, mass-directed prep-HPLC, flash chromatography, LC/SFC-MS, and related platforms.
- Analyze crude reaction mixtures and purified compounds using UPLC/HPLC-UV, LC-MS, and, when needed, NMR.
- Operate an open-access, walk-up LC-MS and purification service with rapid sample assessment and turnaround.
- Track sample identity, recovery, yield, purity, and analytical data throughout purification workflows.
- Perform preventive maintenance, calibration, troubleshooting, and vendor coordination for analytical and preparative instruments and software.
- Maintain compliant records, follow laboratory safety and waste procedures, and contribute to workflow improvement and cross-team projects.
Requirements
- Bachelor’s degree in Chemistry, Analytical Chemistry, Organic Chemistry, Biochemistry, or a related discipline.
- Hands-on experience with analytical and preparative chromatography, including HPLC/UPLC and prep-HPLC.
- Working knowledge of reverse-phase and normal-phase chromatography, mobile and stationary phase selection, and related chemistry.
- Strong attention to detail, disciplined sample tracking, data integrity habits, and the ability to manage high sample throughput.
- Strong written and verbal communication skills with the ability to work independently and collaboratively.
- Ability to work onsite in a laboratory environment, stand for extended periods, and lift laboratory items weighing up to approximately 40 pounds.
Nice to have
- Bachelor’s degree with 1–3+ years of relevant industry experience, or a master’s degree with 0+ years of experience.
- Experience operating and troubleshooting chromatography and mass spectrometry hardware and software.
- Experience with LC-MS, GC-MS, MS-MS, mass-directed preparative purification, automated open-access platforms, or NMR interpretation.
- Experience supporting medicinal chemistry or small-molecule drug discovery programs in a pharmaceutical or CRO setting.
- Familiarity with instrument automation, electronic laboratory notebooks, and chromatography data systems.
Culture & Benefits
- Collaborative environment connecting computational, experimental, chemistry, automation, and nanotechnology teams.
- Work on internal immunology programs and partnerships across multiple therapeutic areas.
- Stock option plan and a 3% retirement safe harbor contribution.
- Fully paid health, dental, and vision insurance for employees and eligible family members.
- Life insurance, disability coverage, and additional benefits.
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