Senior Associate Scientist (Organic Synthesis)

Location: Onsite at the hirify.global Therapeutics headquarters in San Diego, United States

Salary: $84,000–$105,000 annually for Sr Associate Scientist I; $96,000–$120,000 annually for Sr Associate Scientist II

Company

hirify.global Therapeutics is a clinical-stage life-science and technology company developing medicines through an AI-driven discovery and development platform.

What you will do

• Design, synthesize, purify, and characterize chemical compounds at 10 mg–5 g scale using LCMS, HPLC, NMR, and automated parallel synthesis.
• Identify and optimize reaction conditions using screening kits and streamlined methodologies.
• Collaborate with the high-throughput experimentation team to execute parallel chemistry experiments.
• Analyze biological and ADME-PK data with cheminformatics tools and contribute to data-driven project planning.
• Partner with computational chemists to apply machine learning insights to the design–make–test cycle and platform development.
• Present results, implications, and recommendations to project teams and senior leadership.

Requirements

• BS in Chemistry with 5+ years of pharmaceutical or biotechnology experience, or MS in Chemistry with 3+ years of relevant experience.
• Proven experience in multi-step organic synthesis, reaction optimization, SAR analysis, and scientific presentation.
• Hands-on experience in drug discovery and a strong drug hunter mindset.
• Ability to work in a fast-paced, highly collaborative research environment.
• Availability to work onsite in San Diego is required.

Nice to have

• Experience with high-throughput experimentation.
• Familiarity with ADME-PK principles.
• 5+ years contributing to drug discovery projects.
• Experience with molecular modeling and structure-based drug design.

Culture & Benefits

• Cross-functional collaboration across chemistry, biology, DMPK, computational chemistry, machine learning, and software engineering.
• Company-paid healthcare and flexible spending accounts.
• Voluntary life insurance and 401(k) matching.
• Uncapped vacation.
• Work in a new state-of-the-art San Diego facility with an onsite gym and dining.
• Inclusive environment focused on diversity and collaborative scientific innovation.