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19 часов назад

Associate Scientist/Scientist I, Translational Biology

88 000 - 144 000$
Формат работы
onsite
Тип работы
fulltime
Грейд
junior/middle
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Associate Scientist/Scientist I, Translational Biology (Flow Cytometry/LNP): Developing cross-species flow cytometry, tissue-processing, and immunoassay workflows to evaluate lipid nanoparticle delivery, immune activation, and therapeutic function with an accent on high-dimensional panels, viable cell isolation, and high-throughput screening. Focus on interpreting complex cytometry data, optimizing assays across preclinical species, and translating results into experimental strategy within AI-enabled scientific discovery workflows.

Location: Cambridge, MA, USA; office-based work is indicated for office-based employees.

Expected base salary: $88,000–$144,000 USD annually, with bonus potential and early-stage equity.

Company

hirify.global builds AI-powered scientific systems and automated instruments for autonomous discovery across medicine, materials, and energy.

What you will do

  • Serve as a flow cytometry subject-matter expert, designing and executing high-dimensional multi-parameter panels for LNP uptake, delivery, expression, immune activation, and phenotyping.
  • Process liver, spleen, and whole-blood samples from mouse, rat, NHP, and human studies, generating viable single-cell suspensions for downstream analysis.
  • Develop and run assays using flow cytometry, ELISA, multiplex immunoassays, qPCR, IncuCyte, and other cell biology readouts.
  • Drive high-throughput and plate-based screening with liquid handling and automation teams.
  • Analyze and present data, translate results into experimental strategy, and maintain high-integrity laboratory records.
  • Mentor junior scientists and collaborate with biology, automation, and data teams.

Requirements

  • BS with 5+ years or MS with 3+ years of hands-on laboratory experience in biology, biochemistry, immunology, biomedical engineering, or a related field.
  • Advanced expertise in multi-parameter and spectral flow cytometry, including panel design, fluorophore selection, compensation/unmixing, instrument QC, acquisition, and interpretation.
  • Hands-on FlowJo experience with gating strategy design and multi-parameter analysis.
  • Expertise in ex vivo tissue processing and cell isolation, including perfusion, dissociation, density-gradient separation, and RBC lysis across multiple species.
  • Experience with FACS, bead isolation, automated or plate-based flow acquisition, and electronic laboratory records.
  • Ability to independently troubleshoot experiments, manage concurrent studies, and contribute to assay development.

Nice to have

  • Experience with LNPs, nucleic acid therapeutics, tissue biodistribution, or tissue-resident immune cell analysis.
  • Experience with qPCR, ddPCR, CRO coordination, assay SOPs, validation packages, ELISA development, automation, or liquid handlers.
  • Experience with MSD, Luminex, or ELLA multiplex immunoassays.

Culture & Benefits

  • Full-time U.S. employees receive medical, dental, and vision coverage.
  • Benefits include employer-paid life and disability insurance, flexible time off, company holidays, and paid parental leave.
  • Educational assistance, commuter benefits, bike-share memberships for office-based employees, and a subsidized lunch program are provided.
  • Bonus potential and generous early-stage equity are available.
  • International employees receive benefits tailored to their region.

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