Staff Bioinformatics Scientist (NGS)

Location: US - California - San Diego

Base salary: $155,600–$233,400 per year, plus eligible variable cash compensation and equity.

Company

hirify.global develops genomic technology and the DRAGEN platform for secondary analysis of next-generation sequencing data, supporting applications in disease detection, diagnosis, and treatment research.

What you will do

• Design, prototype, and implement computational and statistical algorithms that extract biological signals from sequencing assays.
• Develop production-grade algorithms in C/C++ for structural variant detection, pangenome references, graph-based analysis, and NGS assembly.
• Contribute to secondary analysis methods covering germline and somatic workflows, DNA and RNA data, and multiple variant classes.
• Collaborate with QC/QA, FPGA, software, and clinical genomics teams.
• Engage with external scientific teams to establish product credibility and define emerging requirements.
• Communicate technical methods and findings to audiences with diverse expertise.

Requirements

• At least 8 years of related experience with a Bachelor’s degree, 6 years with a Master’s degree, or 3 years with a PhD, or equivalent experience.
• Experience developing next-generation sequencing data analysis methods.
• Extensive experience with an object-oriented programming language; C++ is preferred.
• Strong background in computer science algorithms relevant to bioinformatics.
• Ability to use AI-assisted development tools for rapid iteration and prototyping.
• Experience with Git, strong communication skills, and the ability to work independently and collaboratively.

Nice to have

• Experience with multithreading and memory management.
• Knowledge of probability, statistics, or machine learning.
• Experience with bioinformatics tools, software testing, CI/CD, debugging, and agile development.
• Background in NGS assembly, structural variant detection, or cancer-related applications.

Culture & Benefits

• Inclusive environment focused on belonging, openness, collaboration, and diverse perspectives.
• Health, dental, and vision coverage, retirement benefits, paid time off, and family-planning support.
• Access to genomics sequencing and employee resource groups supporting career development and social responsibility.
• Variable cash programs and equity for eligible roles.
• Background checks are conducted after a conditional offer.