3 дня назад
Senior Scientist - PKDM-BA (Biotech)
143 821 - 194 581$
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Описание вакансии
Текст:
TL;DR
Senior Scientist - PKDM-BA (Biotech): Designing and executing biological and biophysical experiments to characterize ADME properties, clearance mechanisms, and biodistribution of large-molecule therapeutics with an accent on assay development, protein therapeutics, and preclinical bioanalysis. Focus on interpreting complex biochemical and biophysical data, translating observations into cellular and animal-based models, and communicating mechanistic insights to drug development teams.
Location: South San Francisco, California, United States; lab-based role
Salary: $143,820.85–$194,581.15 per year
Company
is a biotechnology company developing medicines for serious illnesses across oncology, inflammation, general medicine, and rare disease.
What you will do
- Design and execute biological and biophysical experiments to characterize ADME properties of large-molecule therapeutics and non-traditional small-molecule therapies.
- Develop assays and technologies to define mechanisms of in vivo clearance and biodistribution.
- Interpret experimental data and communicate results to project team representatives.
- Maintain electronic laboratory notebooks and document experimental results.
- Contribute to department strategy for drug candidate teams as a PKDM project representative.
Requirements
- PhD, PharmD, or MD with relevant postdoctoral experience; or a master’s degree with 3 years of related experience; or a bachelor’s degree with 5 years of related experience.
- Degree or equivalent expertise in immunology, cell biology, biochemistry, biophysics, or a related field.
- Experience with protein therapeutics drug discovery and development and a basic understanding of protein therapeutics pharmacokinetics.
- Expertise in protein-protein interaction analysis using modern biophysical techniques.
- Experience with protein biochemistry or cell biology techniques, including reagent preparation, assay development, optimization, and troubleshooting.
- Strong communication, interpersonal, collaboration, and problem-solving skills in a fast-paced environment.
Nice to have
- Experience translating biochemical and biophysical observations into cellular and animal-based models with mechanistic insights.
Culture & Benefits
- Collaborative, innovative, science-based work environment.
- Health, dental, vision, life, disability, and flexible spending benefits.
- Retirement and savings plan with company contributions.
- Annual bonus program and stock-based long-term incentives.
- Paid time off and career development opportunities.
- Visa sponsorship is not guaranteed.
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