6 дней назад
Sr. Bioinformatics Developer (Cancer Genomics)
84 577 - 135 224$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Sr. Bioinformatics Developer (Cancer Genomics): Building end-to-end pipelines that harmonize clinical molecular testing data and load standardized genomic datasets into cBioPortal, OMOP Genomics Extensions, and analytics platforms with an accent on cancer genomics, variant standardization, and clinical data integration. Focus on designing scalable transformation workflows, validating genomic data quality, and supporting precision medicine, translational research, and AI/ML-based risk assessment.
Location: NYU Grossman School of Medicine, United States
Salary: $84,577.93–$135,224.49 annually
Company
is an academic medical center focused on medical education, scientific research, and direct patient care.
What you will do
- Design, develop, and implement end-to-end pipelines for harmonizing molecular testing data from Foundation Medicine, Guardant Health, Tempus, and in-house platforms.
- Process VCF, XML, and BAM files across somatic, germline, liquid biopsy, and solid tumor testing workflows.
- Convert vendor-specific data into standardized formats, map variants using HGVS nomenclature, and implement annotation and validation workflows.
- Build automated pipelines that load genomic data into cBioPortal, OMOP-CDM genomics extensions, Tableau, and other analytics platforms.
- Support precision medicine, translational research, clinical trial matching, biomarker discovery, and AI/ML-based risk assessment initiatives.
- Lead requirements analysis, architecture design, technical documentation, production deployment, training, and knowledge transfer.
Requirements
- Master’s degree in Bioinformatics, Computational Biology, Computer Science, or a related field; PhD preferred.
- 5+ years of hands-on experience developing bioinformatics pipelines for genomic data processing.
- Expert Python skills and strong experience with VCF, BAM, XML, variant annotation, HGVS, and clinical cancer genomics data.
- Demonstrated experience with cBioPortal data integration, data models, file formats, loading, and validation.
- Proficiency with SQL and relational databases such as MySQL or PostgreSQL, plus Git/GitHub and collaborative software development.
- Knowledge of OMOP Common Data Model concepts, clinical molecular testing, precision medicine, and translational research.
Nice to have
- Experience with Nextflow, Snakemake, Apache Airflow, Docker, Kubernetes, Java, cloud platforms, or Tableau.
- Experience with machine learning frameworks such as scikit-learn, TensorFlow, or PyTorch.
- Knowledge of R, pandas, SciPy, OncoKB, CIViC, ClinVar, pharmacogenomics, and targeted therapy selection.
Culture & Benefits
- Work within an academic medical center supporting medical education, scientific research, and patient care.
- Access to comprehensive benefits and wellness programs covering financial, physical, mental, nutritional, sleep, social, and preventive care.
- Generous time-off programs, employee resource groups, retirement support, and family-oriented resources.
- Inclusive workplace committed to equity, inclusion, and equal employment opportunity.
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