11 дней назад
Formulation/Process Senior Scientist (LNP)
72 500 - 115 230€
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Formulation/Process Senior Scientist (LNP) (Parenterals and Liquid Development): Developing and optimizing parenteral and liquid drug product formulations and manufacturing processes for LNP and targeted LNP delivery of RNA therapeutics with an accent on nanoparticle formation, TFF, conjugation, sterile filtration, and fill-finish. Focus on hands-on laboratory development, scale-up, technology transfer, clinical manufacturing, and translating advanced delivery technologies into clinical and commercial products.
Location: Beerse, Antwerp, Belgium; onsite
Base pay: €72,500–€115,230 per year
Company
Johnson & Johnson MedTech develops healthcare and pharmaceutical solutions, including innovative medicines and advanced drug delivery technologies.
What you will do
- Develop and optimize parenteral and liquid drug product formulations and processes, with a primary focus on LNP and targeted LNP systems for RNA and other advanced therapeutics.
- Develop LNP manufacturing processes covering nanoparticle formation, tangential flow filtration, conjugation, sterile filtration, and fill-finish considerations.
- Conduct hands-on laboratory experiments and document results in electronic laboratory notebooks and technical reports.
- Provide technical leadership for scale-up, technology transfer, clinical manufacturing, regulatory submissions, patent applications, and related documentation.
- Collaborate with RNA drug substance, protein, chemistry, process engineering, analytical development, pharmaceutical sciences, supply teams, CDMOs, academic partners, and other external organizations.
- Evaluate scientific literature and emerging manufacturing and drug delivery technologies and translate findings into patient-focused development solutions.
Requirements
- Bachelor’s degree in Pharmaceutical or Chemical Engineering or Biochemistry with 6 years of experience, Master’s degree with 4 years of experience, or PhD with 2 years of experience.
- Hands-on experience in parenteral or liquid formulation and process development for LNP and/or targeted LNP systems delivering RNA or other advanced therapeutics.
- Ability to perform accurate and safe laboratory experiments in a modern laboratory environment.
- Strong critical thinking, problem-solving, scientific curiosity, innovation, accountability, and adaptability.
- Strong oral and written communication skills and the ability to collaborate with internal teams, external partners, academic networks, and CDMOs.
- Ability to work onsite in Beerse, Belgium.
Nice to have
- Expertise in LNP characterization, scale-up, and manufacturing technologies.
- Experience with microfluidic or mixing technologies, TFF process development, and conjugation technologies for targeted delivery.
- Background in liposomes, biodegradable microspheres, nanosuspensions, injectable biodegradable rods, or in-situ gels.
Culture & Benefits
- Work in a multidisciplinary drug product research and development environment spanning early discovery through commercialization.
- Vacation days, parental leave of at least 12 weeks, bereavement leave, caregiver leave, and volunteer leave.
- Well-being reimbursement and programs supporting financial, physical, and mental health.
- Annual bonus with a target determined by pay grade and location.
- Insurance plans, service anniversary awards, and recognition programs subject to applicable plan terms.
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