7 дней назад
2027 Spring Co-op Bioanalytics
57$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
2027 Spring Co-op Bioanalytics (LC-MS/PK/PD): Developing and qualifying bioanalytical assays for non-clinical pharmacokinetic and pharmacodynamic studies, with an accent on LC-MS/MS, LC-HRMS, protein analysis, and sample preparation. Focus on characterizing biologics and antibody oligonucleotide conjugates, analyzing biological samples, and interpreting bioanalytical data for drug development.
Location: Cambridge, Massachusetts, United States; onsite; relocation to the office and 40 hours per week, Monday-Friday, for the full six-month co-op required
Salary: $57 per hour
Company
R&D-driven, AI-powered biopharma company developing medicines and vaccines through translational science and an innovative research pipeline.
What you will do
- Design, develop, and fit-for-purpose qualify preclinical PK LC-MS assays for biologics and antibody oligonucleotide conjugates.
- Develop sample preparation methods, including protein precipitation, solid-phase extraction, immunoprecipitation, and enzymatic digestion.
- Develop LC-MS/MS and LC-HRMS methods for intact protein, middle-up, and bottom-up analysis.
- Characterize pharmacokinetic profiles and construct integrity in discovery and preclinical studies.
- Analyze samples and report bioanalytical and biomarker results in the context of drug development.
- Contribute to scientific discussions and collaborate with allied functions on first-in-human dose predictions.
Requirements
- Currently pursuing a PhD in biochemistry, biotechnology, pharmaceutical sciences, or a related health science, with expected graduation by December 2028.
- Permanent authorization to work in the United States without current or future employment visa sponsorship required; CPT, OPT, and STEM OPT generally do not qualify unless an alternative long-term status is available.
- Enrollment at an accredited college or university throughout the co-op and ability to relocate to Cambridge and work onsite full time.
- Knowledge of pharmacokinetics and pharmacodynamics and their role in drug development.
- Expertise in at least one mass spectrometry platform and protein analysis using Thermo, Waters, or Sciex systems.
- Experience with protein extraction from biological matrices and knowledge of proteomics tools, protein database queries, and sequence analysis.
Nice to have
- Experience using artificial intelligence tools for drug discovery and development.
- Experience independently developing or qualifying bioanalytical assays.
- Strong problem-solving, organization, documentation, communication, and teamwork skills.
Culture & Benefits
- Mentoring and guidance from experienced scientific leaders.
- Collaborative work on real healthcare and drug development projects.
- Access to modern scientific tools, digital innovation, and continuous learning.
- Opportunities to develop through internships, graduate programs, apprenticeships, and international experiences.
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