9 дней назад
Scientist (Biotech)
129 404 - 175 076$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Scientist (Biotech): Developing and applying tissue-based assays for target expression, preclinical models, pharmacodynamics, efficacy, and biomarker discovery with an accent on multiplex histopathology, digital pathology, and image analysis. Focus on optimizing IHC and ISH methods, analyzing whole-slide imaging data, and applying machine-learning approaches to tissue-image interpretation.
Location: US - California - South San Francisco
Salary: $129,404–$175,076 per year
Company
is a biotechnology company developing medicines across oncology, inflammation, general medicine, and rare disease.
What you will do
- Develop, optimize, validate, and standardize tissue-based histopathology assays using FFPE samples.
- Apply single-plex and multiplex immunohistochemistry, in situ hybridization, and immunofluorescence methods.
- Generate, analyze, and interpret tissue-based data using imaging modalities and digital pathology tools.
- Support target qualification, pharmacodynamic and efficacy assessments, preclinical model development, toxicity assessments, and biomarker discovery.
- Collaborate with pathologists, research investigators, and translational teams across therapeutic areas.
- Document results in laboratory information systems and databases and communicate findings through presentations.
Requirements
- Doctorate degree, or a master’s degree with 2+ years of relevant research and industry experience, or a bachelor’s degree with 4 years of relevant research and industry experience.
- Degree in cell biology, molecular biology, or a related discipline.
- Experience with pathology-based methods including IHC, multiplex IHC, ISH, and immunofluorescence imaging.
- Experience analyzing H&E, IHC, multiplex immunofluorescence, and/or spatial transcriptomics data.
- Understanding of machine-learning methods for image segmentation, classification, detection, and representation learning.
- Strong communication, organizational, and collaboration skills in multidisciplinary scientific environments.
Nice to have
- Two or more years of molecular pathology experience, preferably in an industry setting.
- Experience with HALO or Visiopharm digital pathology and image-analysis platforms.
- Experience with automated staining platforms such as Ventana, Leica Bond, or IntelliPATH.
- Ability to manage multiple projects and priorities simultaneously.
Culture & Benefits
- Collaborative, innovative, and science-based work environment.
- Health, dental, vision, life, disability, and flexible spending benefits.
- Retirement and savings plan with company contributions.
- Discretionary annual bonus program and stock-based long-term incentives.
- Paid time off and career development opportunities.
- Visa sponsorship is not guaranteed.
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