8 дней назад
Scientific Associate Director - Safety Pharmacology (Biotech)
194 274 - 262 842$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Scientific Associate Director - Safety Pharmacology (Biotech): Leading cardiac safety and electrophysiology laboratory activities, safety issue resolution studies, and cross-functional pharmacology strategy with an accent on in vitro and in vivo assessment, human-relevant models, and clinical translation. Focus on managing scientific staff and GLP studies, integrating data across assay systems and modalities, and guiding regulatory strategy for small molecules, biologics, and emerging therapeutics.
Location: Thousand Oaks, California, United States
Salary: $194,274.30–$262,841.70 annual
Company
is a biotechnology company developing and manufacturing innovative medicines across oncology, inflammation, general medicine, and rare disease.
What you will do
- Lead the cardiac safety and electrophysiology laboratory, including ion channel, hiPSC-derived cardiomyocyte, and isolated heart assays.
- Manage exploratory and GLP-compliant studies, including protocol development, outsourcing, data review, quality control, and report finalization.
- Supervise scientific staff and ensure timely, high-quality data generation, study tracking, reporting, and stakeholder communication.
- Serve as a Safety Pharmacology subject matter expert on discovery and development project teams.
- Design and interpret safety studies, integrate in vitro and in silico data, and support candidate selection, risk assessment, clinical translation, and regulatory filings.
- Build external scientific collaborations and advance human-relevant safety models, publications, presentations, and industry best practices.
Requirements
- Doctorate degree with 4 years of relevant scientific experience, or master’s degree with 7 years, or bachelor’s degree with 9 years.
- PhD in pharmacology, neuroscience, physiology, biomedical sciences, or a related field is preferred.
- Broad experience in in vitro and/or in vivo safety pharmacology across cardiovascular, respiratory, and CNS domains.
- Working knowledge of cardiac ion channel assays, including hERG, Nav1.5, and Cav1.2, as well as hiPSC-derived cardiomyocyte and isolated heart assays.
- Experience with outsourced studies, CRO relationships, GLP-enabling safety pharmacology packages, and cross-functional project teams.
- Demonstrated people leadership, laboratory management, scientific communication, and problem-solving skills.
Culture & Benefits
- Collaborative, innovative, and science-based work environment.
- Health, dental, and vision coverage, life and disability insurance, and flexible spending accounts.
- Retirement and savings plan with company contributions.
- Discretionary annual bonus and stock-based long-term incentives.
- Paid time-off plans and career development opportunities.
- Sponsorship is not guaranteed.
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