5 дней назад
Senior Associate Scientist, ADC In Vivo Pharmacology
68 600 - 114 300$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Associate Scientist, ADC In Vivo Pharmacology (ADC/Oncology): Executing in vivo oncology studies for antibody-drug conjugate discovery and preclinical development with an accent on efficacy, tolerability, pharmacodynamic assessment, and sample collection. Focus on administering test articles across rodent models, monitoring tumors and animal welfare, maintaining compliant study records, and coordinating multidisciplinary study execution.
Location: San Diego, California, United States; on-premise. Relocation support may be available based on business needs and eligibility. Permanent U.S. work authorization is required; visa sponsorship is not available.
Annual base salary: $68,600–$114,300, plus eligibility for a 7.5% performance bonus.
Company
conducts pharmaceutical research and development, including oncology discovery and preclinical development.
What you will do
- Execute in vivo oncology studies supporting ADC, large-molecule, and small-molecule discovery programs.
- Perform rodent procedures including tumor measurements, body-weight monitoring, clinical observations, dosing, and sample collection.
- Support efficacy, tolerability, pharmacodynamic biomarker, dosing-schedule, and combination studies.
- Prepare study materials, verify dosing and sampling schedules, and follow approved protocols and SOPs.
- Maintain accurate study records and communicate observations, technical issues, animal-welfare concerns, and timeline risks.
- Collaborate with vivarium operations, pathology, bioanalytical, pharmacodynamic, pharmacokinetic, and project teams.
Requirements
- Bachelor’s degree in biology, pharmacology, animal science, cancer biology, or a related discipline, or equivalent laboratory experience.
- Hands-on rodent handling and in vivo research experience.
- Working proficiency in tumor measurement, animal monitoring, IV, PO, subcutaneous and intraperitoneal dosing support, sample collection, and study documentation.
- Understanding of oncology pharmacology, tumor growth, treatment response, tolerability monitoring, and pharmacodynamic endpoints.
- Strong organization, communication, collaboration, and attention to detail.
- Must be authorized to work in the United States by any employer and hold permanent U.S. work authorization.
Nice to have
- Experience with ADC, targeted therapy, immuno-oncology, or oncology combination studies.
- Knowledge of ADC target antigen expression, payload activity, linker stability, exposure-response relationships, and tolerability.
- Experience with necropsy, tissue or blood collection, biomarker processing, flow cytometry, cell-line assays, or molecular and biochemical procedures.
- Familiarity with Studylog or similar electronic in vivo study management systems.
- AALAS certification or equivalent animal care and use training.
Culture & Benefits
- On-premise laboratory and vivarium work with a commitment to animal welfare, biosafety, compliance, and high-quality study execution.
- Comprehensive medical, prescription drug, dental, and vision coverage.
- 401(k) matching and an additional retirement savings contribution.
- Paid vacation, holidays, personal days, and caregiver, parental, and medical leave.
- Some weekend work may be required.
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