7 дней назад
Senior Research Associate, In Vivo Pharm (Autoimmune Pharmacology)
74 000 - 118 400$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Research Associate, In Vivo Pharm (Autoimmune Pharmacology): Executing vivarium-based in vivo studies for autoimmune disease programs with an accent on immune cell modulation, inflammatory readouts, pharmacokinetics, pharmacodynamics, and therapeutic efficacy. Focus on performing complex dosing and tissue-collection procedures, coordinating study logistics, interpreting preclinical data, and maintaining IACUC-compliant documentation.
Location: Cambridge, Massachusetts, United States; 70% in-office work model
Salary: $74,000–$118,400 per year, with potential discretionary bonus, incentive compensation, or equity.
Company
develops mRNA-based therapeutics and vaccines across infectious diseases, immuno-oncology, rare diseases, and cardiovascular diseases.
What you will do
- Execute in vivo studies supporting autoimmune disease programs, including immune cell modulation, inflammatory readouts, pharmacokinetics, pharmacodynamics, and therapeutic efficacy.
- Perform mouse handling, compound administration by IM, IP, IV, and SC routes, blood and tissue collection, necropsy, and clinical observations.
- Support study design, endpoint selection, data interpretation, troubleshooting, and communication with research partners.
- Coordinate dosing schedules, sample collection plans, reagent preparation, and other study logistics.
- Analyze, visualize, and summarize study data using established tools and templates.
- Maintain protocols, sample inventories, study records, and summaries in compliance with IACUC, animal welfare, biosafety, and institutional requirements.
Requirements
- Bachelor’s or Master’s degree in Biology, Immunology, Pharmacology, or a related discipline.
- At least 2 years of hands-on in vivo research experience; 4+ years is preferred for advanced experience.
- Experience with mouse handling, dosing, blood collection, tissue harvest, necropsy, and clinical monitoring.
- Strong attention to detail, data quality, documentation, reproducibility, and protocol compliance.
- Ability to manage multiple tasks and collaborate effectively in a fast-paced scientific environment.
- Hands-on vivarium work is required; holiday and weekend work may be necessary.
Nice to have
- Experience with autoimmune or inflammatory disease models.
- Familiarity with oncology or immuno-oncology models.
- Proficiency with GraphPad Prism and Excel.
- Experience with Benchling In Vivo.
Culture & Benefits
- In-person collaboration with a 70/30 work model focused on teamwork, innovation, and mentorship.
- Healthcare coverage and voluntary benefit programs.
- Fitness, mindfulness, mental health, family planning, fertility, adoption, and surrogacy support.
- Paid vacation, volunteer days, sabbatical, global recharge days, and discretionary year-end shutdown.
- Savings and investment programs, plus location-specific benefits.
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