9 дней назад
Scientist, Neuromuscular Research
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Scientist, Neuromuscular Research (Biotechnology): Advancing neuromuscular disorder research through disease-mechanism studies, therapeutic-target discovery, and candidate evaluation with an accent on iPSC-derived and primary human muscle models, molecular and cellular assays, and rodent disease models. Focus on designing and interpreting experiments, measuring in vivo muscle function, and translating findings into therapeutic research programs.
Location: Cambridge, Massachusetts, United States
Company
is a mid-sized biotechnology company developing life-changing medicines and advancing research in neuromuscular disorders.
What you will do
- Design, execute, analyze, and interpret experiments supporting neuromuscular research programs.
- Develop and optimize molecular and cellular assays using iPSC-derived and primary human skeletal muscle and cardiac disease models.
- Characterize muscle disease phenotypes in rodent models and evaluate therapeutic activity and mechanisms of action.
- Present research findings in team meetings and cross-functional forums.
- Collaborate with internal teams and external research partners.
Requirements
- PhD with 0–2+ years of relevant academic or industry experience in muscle biology, physiology, or a related field.
- Strong background in muscle biology, disease pathophysiology, and translational research.
- Hands-on experience with iPSC-derived and primary human myotube and cardiomyocyte culture.
- Experience assessing in vivo muscle function, including evoked force, treadmill, and related endpoints in neuromuscular disease models.
- Experience with biochemistry, molecular biology, statistical analysis, and GraphPad Prism or similar software.
- Ability to independently design, execute, troubleshoot, and communicate experimental results.
Nice to have
- Experience with genetic neuromuscular disorders such as DMD and DM1.
- Direct experience with RNA therapies, antisense oligonucleotides, or LNP.
- Strong record of scientific publications and presentations.
Culture & Benefits
- Medical, dental, vision, and life insurance.
- Fitness and wellness programs, including fitness reimbursement.
- Paid vacation, company holidays, sick time, and end-of-year shutdown leave.
- Paid maternity and parental leave, short- and long-term disability insurance, and 401(k) matching.
- Employee stock purchase plan, equity opportunities, tuition reimbursement, and employee resource groups.
- Employment is based in the United States and is subject to US employment verification.
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