1 день назад
Senior Scientist (I/O) In Vitro/Ex Vivo
153 000 - 170 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Scientist (I/O) In Vitro/Ex Vivo (Immuno-Oncology): Developing and evaluating novel immune therapies through in vitro and ex vivo studies using primary immune cells, tumor cell lines, reporter systems, and co-culture models with an accent on functional immune assays and multicolor flow cytometry. Focus on designing complex experiments, interpreting mechanisms of action, troubleshooting assay systems, and delivering data-driven recommendations for biologic drug development.
Location: Weston, Massachusetts, United States
Salary: $153,000–$170,000 per year
Company
is a clinical-stage biopharmaceutical company developing multispecific biologics for cancer and infectious diseases.
What you will do
- Develop and evaluate biologic drug candidates for immunotherapy and immunology programs.
- Design, execute, analyze, and interpret in vitro and ex vivo studies using primary human and mouse immune cells.
- Develop complex immune cell-based functional assays with tumor cell lines, reporter systems, and co-culture models.
- Design, optimize, and troubleshoot multicolor flow cytometry panels, including compensation, unmixing, antibody titration, and gating strategies.
- Generate data-driven conclusions and recommendations to advance research programs.
- Collaborate with discovery, translational, and project teams; prepare scientific reports and presentations; and maintain accurate experimental documentation.
Requirements
- Ph.D. or M.S. in Immunology, Cancer Biology, Cell Biology, Immuno-Oncology, or a related field.
- 10+ years of relevant research experience, including at least 4 years in a biotechnology or pharmaceutical R&D environment.
- Hands-on expertise in immunotherapy, immunology, primary immune cell assays, multi-parameter flow cytometry, and cytokine profiling.
- Experience with immune activation, proliferation, and cytotoxicity assays, as well as flow cytometry panel design and data analysis.
- Ability to work independently, prioritize effectively, troubleshoot experiments, and advance projects in a fast-paced biotech environment.
- Strong written and oral communication, organization, problem-solving, collaboration, and mentoring skills.
Nice to have
- Experience with spectral flow cytometry.
Culture & Benefits
- Collaborative, cross-functional work across discovery, translational, and project teams.
- Opportunity to contribute to next-generation therapeutics for cancer and infectious diseases.
- Work in a fast-paced, rapidly growing clinical-stage biotechnology environment.
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