Associate Principal Scientist, Regenerative Immunology

Location: Englewood, New Jersey, United States. Candidates must be able to work in the United States without sponsorship.

Starting base pay: $160,000–$215,000 per year. Additional compensation: $10,000–$20,000 per year.

Company

hirify.global is a privately funded biotechnology company developing regenerative and preventive personalized medicine interventions for biological aging and age-related diseases.

What you will do

• Lead the Thymic Regeneration Team developing iPSC-derived thymic epithelial cells and thymic organoids.
• Design and optimize directed-differentiation protocols to generate functional thymic epithelial cells from human iPSCs.
• Advance practical approaches to thymic regeneration, immune reconstitution, and rejuvenative medicine.
• Collaborate with scientists and research groups on personalized immune rejuvenation programs.

Requirements

• PhD or MD/PhD.
• At least 10 years of research experience, preferably in thymic biology, stem cell differentiation, organoid engineering, or regenerative immunology.
• In-depth knowledge of thymic epithelial cell biology, iPSC directed differentiation, T-cell development, and tissue engineering.
• Expertise in experimental therapeutics and interventions addressing age-related immune senescence and immune regeneration.
• Ability to work in the United States without sponsorship.

Nice to have

• Knowledge of thymic epithelial cell ontogeny, FOXN1 biology, T-cell selection, and thymic niche reconstitution.
• Experience with iPSC culture, 3D organoid culture, single-cell genomics, RNA sequencing, flow cytometry, immunofluorescent microscopy, CRISPR gene editing, and cell culture.
• Experience with in vivo transplantation, humanized mouse models, and functional immune reconstitution assessment.

Culture & Benefits

• Small-group, highly collaborative research environment.
• State-of-the-art resources for scientific work.
• Small teams are empowered to advance regenerative medicine research.