8 дней назад
Senior Associate Scientist, ADC In Vivo Pharmacology
68 600 - 114 300$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Associate Scientist, ADC In Vivo Pharmacology (Oncology/ADC): Conducting in vivo oncology studies supporting antibody-drug conjugate discovery and preclinical development with an accent on efficacy, tolerability, pharmacodynamic assessment, and sample collection. Focus on executing xenograft and syngeneic models, maintaining compliant study records, and coordinating animal welfare and study integrity across multidisciplinary teams.
Location: On premise in San Diego, California, United States. Must be authorized to work in the United States by any employer; U.S. work visa sponsorship is not available.
Annual base salary: $68,600–$114,300, plus eligibility for a 7.5% bonus target.
Company
conducts pharmaceutical research and development, including oncology and antibody-drug conjugate programs.
What you will do
- Conduct routine in vivo oncology activities, including tumor measurements, body weight monitoring, clinical observations, dosing support, and sample collection.
- Assist with xenograft, syngeneic, and other oncology models under established protocols.
- Support studies evaluating ADC efficacy, tolerability, pharmacodynamic biomarkers, dosing schedules, and combination approaches.
- Prepare study materials, confirm dosing and sampling schedules, and follow approved protocols and SOPs.
- Maintain accurate study records and communicate observations, technical issues, animal welfare concerns, and timeline risks.
- Collaborate with vivarium operations, pathology, bioanalytical, pharmacodynamic, pharmacokinetic, and project teams.
Requirements
- Bachelor’s degree in biology, pharmacology, animal science, cancer biology, or a related discipline, or equivalent laboratory experience.
- Hands-on experience with rodent handling and in vivo procedures in a research, biotechnology, pharmaceutical, academic, or contract research setting.
- Working proficiency in tumor measurement, animal monitoring, dosing support, sample collection, and study documentation.
- Ability to follow protocols, dosing schedules, sampling plans, and SOPs with precision.
- Basic understanding of oncology pharmacology, tumor growth, treatment response, tolerability monitoring, and pharmacodynamic endpoints.
- Strong organization, communication, accountability, and collaboration skills.
Nice to have
- Experience with ADC, targeted therapy, immuno-oncology, or oncology combination studies.
- Knowledge of ADC pharmacology, including target antigen expression, payload activity, linker stability, exposure-response relationships, and tolerability.
- Experience with necropsy, tissue or blood collection, biomarker sample processing, or ex vivo endpoints.
- Familiarity with Studylog or similar electronic in vivo study management systems.
- AALAS certification or equivalent animal care and use training.
Culture & Benefits
- Full-time, on-premise work supporting multidisciplinary oncology research.
- Willingness to work after hours when needed to maintain study integrity.
- Relocation assistance may be available based on business needs and eligibility.
- Benefits include 401(k) contributions, paid vacation and holidays, caregiver and medical leave, and medical, prescription, dental, and vision coverage.
- Participation in ’s Global Performance Plan with a 7.5% bonus target.
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