6 дней назад
Principal Scientist, Flow Cytometry
110 700 - 166 100$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Principal Scientist, Flow Cytometry (Immunophenotyping and Cell-Based Assays): Designing and validating high-content flow cytometry, receptor occupancy, tetramer/dextramer, ELISpot, and other custom cell-based assays for translational medicine research with an accent on immuno-oncology, autoimmune and inflammatory studies, and regulatory compliance. Focus on leading assay development, troubleshooting complex laboratory workflows, training scientific staff, communicating results to biopharmaceutical clients, and building validation strategies under GLP, CAP, and CLIA requirements.
Location: Frederick, MD, USA
Salary: $110,700–$166,100 USD per year, plus eligibility for a discretionary annual bonus.
Company
delivers laboratory and translational medicine services to biopharmaceutical clients.
What you will do
- Design and implement qualified and validated immunophenotyping and custom cell-based assays, including high-content flow cytometry, receptor occupancy, tetramer/dextramer, ELISpot, and Fluorospot assays.
- Develop experimental plans, timelines, standard operating procedures, and validation schemes aligned with client requirements and applicable regulations.
- Execute assays, troubleshoot laboratory workflows, analyze data, and prepare technical reports, client communications, posters, papers, reviews, and white papers.
- Provide technical expertise on flow cytometry, cell sorting, primary cell assays, and laboratory quality and efficiency.
- Mentor, coach, and train flow laboratory scientists and technical staff in laboratory procedures, data review, and scientific communication.
- Act as an internal subject-matter expert on technical advances and industry trends while supporting client proposals, partnerships, recruitment, and revenue forecasting.
Requirements
- Ph.D. in life sciences or a related field, preferably immunology or cellular biology.
- At least 8 years of full-time post-doctoral laboratory experience.
- Hands-on flow cytometry and cell-based assay experience, including cell isolation and primary cell assays; ELISpot experience is preferred.
- Experience with cell sorting, assay qualification and validation under CAP, CLIA, GLP, or ISO guidelines, troubleshooting, technical reporting, and client relationships.
- Fluent English reading, writing, speaking, and comprehension required.
- Ability to differentiate the full color spectrum and perform laboratory physical requirements, including lifting and working in freezer environments from -20°C to -196°C.
Nice to have
- 10–15+ years of experience as a core laboratory member, including direct management of a flow cytometry team.
- Industrial experience or management of external collaborations.
- Experience with viral infections, cell culture, cell line derivation, nucleic acid extraction from primary human samples, and spectrophotometric, Agilent, or fluorescence-based characterization.
Culture & Benefits
- Work supporting diverse, innovative, and global biopharmaceutical clients.
- Health insurance, retirement savings benefits, life insurance, and disability benefits.
- Parental leave and paid sick leave and vacation.
- Opportunities to promote scientific work through networking, speaking engagements, professional associations, conferences, and publications.
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