9 дней назад
Scientist, Cardiac Vascular - In Vivo (Biotechnology)
93 900 - 153 300$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Scientist, Cardiac Vascular - In Vivo (Biotechnology): Designing and executing longitudinal in-vivo rodent studies for cardiovascular disease programs with an accent on cardiac and vascular surgery, precision dosing, telemetry, and functional data generation. Focus on performing TAC and myocardial infarction models, invasive PV-loop assessments, Langendorff perfusion, and analyzing physiological data for target validation and therapeutic development.
Location: Tarrytown, New York, United States; onsite
Salary: $93,900–$153,300 annually
Company
is a biotechnology company that discovers, develops, and commercializes medicines for serious diseases, including cardiovascular and metabolic conditions.
What you will do
- Design and execute longitudinal in-vivo rodent studies supporting cardiovascular disease programs.
- Perform cardiac and vascular surgical models in mice and rats, including TAC, myocardial infarction, and renal/kidney models.
- Administer test articles through IV, SC, and IM routes and implant osmotic minipumps.
- Implant telemetry devices for continuous blood pressure and ECG monitoring and conduct invasive PV-loop hemodynamic assessments.
- Collect and process ex-vivo tissue, including cardiac dissociation through Langendorff perfusion.
- Manage study logistics, animal health monitoring, post-operative care, data analysis, reporting, and collaboration with study directors and therapeutic-area scientists.
Requirements
- BS with 10+ years or MS with 6+ years of relevant experience in physiology, biomedical sciences, veterinary science, or a related field.
- Hands-on expertise in rodent cardiac and vascular surgical models, including TAC, myocardial infarction, and renal/kidney models.
- Experience with rodent dosing, telemetry implantation, blood pressure and ECG monitoring, and invasive PV-loop measurements.
- Experience with Langendorff perfusion, cardiac tissue dissociation, and rodent anatomy, physiology, and survival-surgery best practices.
- Proficiency with PRISM, PONEMAH, or comparable data-analysis software.
- Strong organizational, communication, scientific-rigor, and animal-welfare skills.
Nice to have
- Experience with additional cardiovascular functional-assessment techniques.
- Experience in a GLP or regulated research environment.
Culture & Benefits
- Science-driven environment focused on translating research into medicines.
- Collaboration with cross-functional research teams.
- Comprehensive rewards may include bonuses, equity, retirement benefits, 401(k) matching, insurance, wellness programs, paid time off, and family-support benefits.
- Inclusive workplace with reasonable accommodation available during recruitment where required.
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