10 дней назад
Research Associate (In Vivo Imaging)
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Research Associate (In Vivo Imaging) (Cerebrovascular Research): Leading pre-clinical in vivo imaging studies of pial artery function, vascular smooth muscle calcium signaling, and cerebral blood flow in mouse models relevant to Alzheimer’s disease with an accent on multiphoton microscopy, optical imaging, and vascular physiology. Focus on combining imaging with behavioural assessment, histology, immunohistochemistry, and physiological analysis to investigate neurovascular dysfunction and therapeutic targets in dementia.
Location: Oxford Road, Manchester, United Kingdom
Company
The hosts the Microvascular@Manchester group within the Division of Cardiovascular Sciences and the Geoffrey Jefferson Brain Research Centre.
What you will do
- Lead pre-clinical in vivo imaging studies in mouse models relevant to Alzheimer’s disease.
- Use multiphoton microscopy and optical imaging to assess pial artery function, vascular smooth muscle calcium signaling, and cerebral blood flow.
- Investigate how vascular amyloid-β(1-40) affects arterial constriction, calcium signaling, and cerebral blood flow.
- Apply behavioural assessment, histology, immunohistochemistry, and physiological analysis.
- Develop translational research within a multidisciplinary academic-industry collaboration.
- Publish findings, present internationally, build collaborations, and contribute to future grant applications.
Requirements
- Expertise in pre-clinical in vivo cerebrovascular imaging, vascular physiology, or neurovascular coupling.
- Strong experimental and analytical skills.
- Experience with pre-clinical vascular imaging.
- Interest in mechanisms underlying neurovascular dysfunction in dementia.
- Ability to work within a multidisciplinary research collaboration.
Culture & Benefits
- Generous employer contribution pension.
- 29 days of annual leave plus bank holidays and Christmas closure.
- Ride to work and electric vehicle car schemes.
- Opportunities to publish, present internationally, develop collaborations, and contribute to grant applications.
- Pre-employment screening is required, and employment is conditional on successfully passing the screening.
Hiring process
- Applications close at midnight on the closing date.
- Shortlisting and interviews are handled by the research group.
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