Senior Principal Scientist, Bioprocess Development (Vaccines)

Location: On premise in Pearl River, New York, United States. Candidates must have permanent authorization to work in the United States.

Annual base salary: $124,400–$207,400, plus a 17.5% bonus target and eligibility for a share-based long-term incentive program.

Company

hirify.global is a global biopharmaceutical company developing medicines and vaccines.

What you will do

• Lead the Polysaccharide Fermentation and Purification Development group within Vaccines, Early BioProcess Development.
• Set scientific direction and develop scalable, robust, and transferable upstream and downstream manufacturing processes.
• Define process development strategies for vaccine programs and align technical plans with program objectives, timelines, manufacturability, and regulatory expectations.
• Lead technology transfer to internal and external clinical manufacturing sites, including technical packages, risk assessments, process controls, and troubleshooting plans.
• Adopt emerging bioprocess technologies, automation, digital tools, and data-driven approaches to improve efficiency, quality, scalability, and robustness.
• Mentor scientific staff, build organizational capability, and collaborate with process development, analytical, formulation, quality, regulatory, and manufacturing teams.

Requirements

• PhD in Chemical Engineering, Biochemical Engineering, Bioengineering, Microbiology, Biochemistry, or a related discipline, with at least 8 years of relevant experience.
• Expertise in vaccine process development, preferably involving capsular or exopolysaccharides, conjugate vaccines, bacterial antigens, carrier proteins, or other microbial-based vaccine platforms.
• Hands-on experience with microbial fermentation and polysaccharide recovery and purification processes.
• Knowledge of polysaccharide critical quality attributes, in-process controls, design of experiments, scale-down models, and process characterization.
• Experience preparing development reports, process descriptions, technology-transfer packages, risk assessments, and CMC content, with knowledge of quality-by-design, data integrity, and phase-appropriate regulatory expectations.
• Permanent U.S. work authorization is required; U.S. work visa sponsorship is not available now or in the future.

Culture & Benefits

• Cross-functional, multidisciplinary work across vaccine development and manufacturing organizations.
• Primarily laboratory-based work under standard laboratory conditions, including complex mathematical calculations and data analysis.
• Comprehensive benefits including a 401(k) plan with matching contributions and an additional retirement savings contribution.
• Paid vacation, holidays, personal days, caregiver and parental leave, and medical leave.
• Medical, prescription drug, dental, and vision coverage.
• Relocation assistance may be available based on business needs and eligibility.