Senior Associate Scientist Purification Process Development (AAV)

Location: Waltham, Massachusetts, United States; onsite

Company

hirify.global is an R&D-driven, AI-powered biopharmaceutical company developing medicines and vaccines through immunoscience, advanced data, and digital technologies.

What you will do

• Develop, design, and conduct viral vector purification experiments for AAV and non-viral vector programs.
• Optimize purification conditions, screen media, troubleshoot experiments, and evaluate new technologies to improve yield and process understanding.
• Apply chromatography, filtration, tangential flow filtration, UF/DF, virus clearance, and inactivation operations across relevant scales.
• Support scale-up and manufacturing process implementation, including technology transfer, gap analyses, and risk assessments with internal teams and CDMOs.
• Analyze data, prepare technical reports and presentations, and contribute to manuscripts and patent applications.
• Build cross-functional collaboration and represent the purification process development team internally and externally.

Requirements

• Bachelor’s or master’s degree in chemical engineering, biological or life sciences, or a related field.
• Bachelor’s degree holders need 2+ years of laboratory or related experience; master’s degree holders need 6+ months. Academic and research experience is accepted.
• Knowledge of purification technologies, chromatography principles, separation methods, and downstream unit operations.
• Experience with GLP and detailed laboratory documentation, technical report writing, and learning new viral vector analytical methods.
• Ability to work under minimal supervision, communicate effectively, build cross-functional relationships, and stand at laboratory bench equipment for extended periods.

Nice to have

• Experience with AAV or non-viral vector purification and large-scale manufacturing operations.
• Knowledge of spectrophotometry, ELISA, HPLC, and SDS-PAGE.
• Familiarity with Quality by Design and Design of Experiments for downstream development.
• Experience with virus clearance studies, technology transfers, biosafety level 2 laboratories, gap analyses, and risk assessments.

Culture & Benefits

• Supportive, collaborative, and future-focused R&D environment.
• Opportunities for career growth through promotion or international and lateral moves.
• Health, wellbeing, and prevention programs with high-quality healthcare benefits.
• At least 14 weeks of gender-neutral parental leave.
• Work with AI, data, and digital platforms to advance drug discovery and gene therapy development.