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24 дня назад

Senior Scientist, Stem Cell Model Engineering (Contract) (iPSC)

11 550 310 - 15 626 890CAD
Формат работы
onsite
Тип работы
fulltime
Грейд
senior
Английский
b2
Страна
Canada
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Senior Scientist, Stem Cell Model Engineering (Contract) (iPSC): Developing, optimizing, and validating human iPSC-derived models for target discovery, target validation, and translational research with an accent on reproducible differentiation, quality control, and biologically relevant human cell systems. Focus on building complex multicellular, 3D, and genetically defined models, troubleshooting variability, and scaling workflows across iPSC lines and experimental conditions.

Location: Burnaby, Canada

Salary: CAD 115,503.10–156,268.90 per year

Company

hirify.global is a biotechnology company researching, manufacturing, and delivering medicines for serious diseases across oncology, inflammation, general medicine, and rare disease.

What you will do

  • Develop, optimize, and troubleshoot differentiation of human iPSCs into tissue-relevant cell types.
  • Establish reproducible and scalable differentiation workflows across experiments, iPSC lines, and increasing experimental scale.
  • Define and execute quality-control and validation strategies covering cell identity, differentiation state, maturation, purity, and tissue-specific function.
  • Identify and resolve biological and technical variability in differentiation efficiency, culture conditions, maturation, and phenotype retention.
  • Develop complex human models, including co-cultures, multicellular systems, 3D cultures, organoids, and other tissue-relevant models.
  • Contribute to CRISPR-edited and disease-relevant iPSC models and communicate model performance, limitations, risks, timelines, and readiness to multidisciplinary teams.

Requirements

  • PhD in a related discipline with at least 2 years of experience, MSc with at least 5 years, or BSc with at least 8 years.
  • Hands-on expertise in human iPSC culture and differentiation, including protocol optimization and troubleshooting.
  • Experience differentiating iPSCs into specialized human cell types and understanding quality control for pluripotency, genomic integrity, identity, purity, maturation, and functional phenotype.
  • Experience developing reproducible and scalable cell-based workflows involving multiple cell lines, experimental conditions, screening, automation, or higher-throughput studies.
  • Experience with complex human cell models such as co-cultures, multicellular systems, 3D cultures, organoids, assembloids, or tissue-like models.
  • Work location: Burnaby, Canada.

Nice to have

  • Postdoctoral or industry experience in stem cell biology, developmental biology, cell biology, bioengineering, molecular biology, or a related discipline.
  • Experience across multiple tissue or cell lineages.
  • Experience with CRISPR-based genome editing of iPSCs.

Culture & Benefits

  • Full-time contract position within a collaborative, innovative, and science-based environment.
  • Work focused on developing medicines and human model systems for target discovery, validation, and translational research.
  • Inclusive workplace committed to ethical, respectful, and diverse collaboration.

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