Executive Director, Clinical Pharmacology/Pharmacometrics (Biotech)

Location: Remote, based in the United Kingdom, with required periodic travel

Annual base salary: £136,500–£167,200, plus annual bonus, equity compensation, and benefits.

Company

hirify.global is a clinical-stage TechBio company using an AI-native drug discovery and development platform to advance medicines across oncology, rare disease, neuroscience, immunology, and other therapeutic areas.

What you will do

• Lead clinical pharmacology and pharmacometrics strategy and execution for rare disease and oncology clinical programs.
• Develop clinical pharmacology strategies and serve as the clinical pharmacology lead across programs in clinical development.
• Perform or oversee modeling and simulation to support dose selection, exposure-response analyses, and development decisions.
• Provide clinical pharmacology input into Phase 1–3 studies and dedicated clinical pharmacology studies.
• Author clinical pharmacology sections of Investigator’s Brochures, INDs, NDAs, and other regulatory submissions.
• Collaborate with clinical development, translational, preclinical, DMPK, toxicology, regulatory, biostatistics, and due diligence teams.

Requirements

• Ph.D. in Pharmaceutical Sciences, Pharmacokinetics, or a related discipline; M.D. with clinical pharmacology expertise; or Pharm.D. with a clinical pharmacology fellowship.
• 10+ years of experience in biotech or pharmaceutical drug development.
• Experience leading clinical pharmacology aspects of drug development and managing PK, PK-PD, and PK-safety analyses.
• Proficiency with WinNonlin, Monolix, NONMEM, R, or other modeling software.
• Experience responding to regulatory agency questions, preparing clinical pharmacology regulatory submissions, and attending regulatory meetings.
• Strong collaboration, influencing, conflict-resolution, decision-making, and results-oriented skills.

Nice to have

• Experience in oncology.

Culture & Benefits

• Remote work from the United Kingdom with periodic travel.
• Annual bonus eligibility and equity compensation.
• Comprehensive benefits package.
• Cross-functional collaboration across discovery and clinical development.
• Values centered on integrity, accountability, active learning, urgency, and patient impact.