3 дня назад
Inflammation Research - In Vivo Pharmacology Senior Scientist
123 052 - 166 483$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Inflammation Research - In Vivo Pharmacology Senior Scientist (Inflammation/Preclinical Pharmacology): Designing and executing in vivo pharmacology studies and ex vivo analyses to advance inflammation, autoimmune, and rare disease therapeutics with an accent on rodent disease models, PK-PD relationships, and immune-cell profiling. Focus on leading preclinical experiments, analyzing pharmacology data, managing a direct report, and collaborating with therapeutic-area project teams.
Location: US - California - South San Francisco
Salary: $123,052.80–$166,483.20 annually
Company
is a biotechnology company developing medicines for oncology, inflammation, general medicine, and rare disease programs.
What you will do
- Design, conduct, and lead in vivo preclinical inflammation and autoimmune disease model studies.
- Execute ex vivo analyses and cutting-edge pharmacology experiments supporting the inflammation research pipeline.
- Use animal models and in vivo pharmacology to validate and advance molecules through research programs.
- Analyze and communicate pharmacology and preclinical data to therapeutic-area scientists and project teams.
- Oversee study data quality and analysis, represent pharmacology on pipeline teams, and present results internally and externally.
- Manage up to one scientist or associate scientist direct report.
Requirements
- Doctorate in immunology, biology, pharmacology, or a related discipline; alternatively, a relevant master's degree with 2 years of biotech or pharmaceutical industry experience, or a bachelor's degree with 4 years of such experience.
- Strong hands-on experience with rodent handling and in vivo techniques, including intravenous, intraperitoneal, oral, intradermal, subcutaneous, and intrathecal dosing, bleeds, and necropsy.
- Significant experience designing and executing concurrent in vivo preclinical inflammation or autoimmune disease models, with knowledge of PK-PD relationships.
- Hands-on experience with ELISA, MSD, Western blot, quantitative RT-PCR, tissue protein extraction, and multicolor or spectral flow cytometry.
- Experience collaborating on project teams, leading in vivo contributions, analyzing data, and maintaining accurate records.
- Proficiency with GraphPad Prism, Excel, PowerPoint, and Word.
Nice to have
- Postdoctoral or industry experience.
- Experience with colitis, lupus, arthritis, hepatitis, immune modulation, dermatology, rheumatoid, or respiratory disease models.
- Experience managing an in vivo pharmacology team or direct reports.
- Publication record or significant contribution to a therapeutic program.
Culture & Benefits
- Collaborative, innovative, and science-based research environment.
- Health, dental, vision, life, disability, and flexible spending benefits.
- Retirement and savings plan with company contributions.
- Discretionary annual bonus and stock-based long-term incentives.
- Paid time-off plans and career development opportunities.
- Visa sponsorship is not guaranteed.
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