LCMS Scientist (ADME/DMPK)

Location: St. Charles, Missouri, USA; candidates must be within a commutable distance. Full-time laboratory position working Sunday–Thursday or Saturday–Wednesday, 8:00 PM–5:00 PM.

Company

hirify.global provides analytical testing, contract research, and laboratory services across food, environmental, pharmaceutical, cosmetic, genomics, and clinical science domains.

What you will do

• Develop liquid chromatography–mass spectrometry methods for ADME/DMPK applications and new assay development.
• Conduct production assays, primarily for ADME Toxicology Services, with potential support for BioMAP, Immunosignaling, Ion Channel, and OncoPanel services.
• Troubleshoot and maintain mass spectrometers and HPLC equipment, including Sciex or Waters instrumentation where applicable.
• Support method validation, process improvements, service-line expansion, equipment development, and data management systems.
• Review data and reports for quality control, maintain reproducible documentation, and communicate project updates to internal and external clients.
• Lead small projects and informal sub-teams, train colleagues and end users, and provide cross-functional support.

Requirements

• B.S. with at least 5 years of relevant laboratory experience, M.S. with at least 3 years, Ph.D. with at least 1 year, or an equivalent combination of education and experience.
• Direct experience with LC-MS or LC-UV in a CRO or industry laboratory, particularly for ADME/DMPK applications and biological matrices.
• Experience with analytical method development and optimization, bioanalytical validation concepts, liquid handling, automation, solid-phase extraction, HTS, and large-scale screening.
• Experience working within a Quality Management System and following FDA, ICH, GxP, SOP, documentation, and data-quality requirements.
• Experience with small-team leadership, project management, R&D or innovation programs, technical reporting, statistical analysis, and troubleshooting.
• Must be authorized to work in the United States indefinitely without restriction or sponsorship.

Culture & Benefits

• Full-time employment in a laboratory and team-based environment.
• Medical, dental, and vision coverage.
• Life and disability insurance.
• 401(k) plan with company match.
• Paid vacation and holidays.