Research Scientist, Purification & Analytical Sciences

Location: On-site at the San Diego Headquarters, United States

Salary: $113,600–$142,000 for Research Scientist I; $124,800–$156,000 for Research Scientist II

Company

hirify.global is a clinical-stage life-science and technology company developing medicines through an AI-driven drug discovery and development platform.

What you will do

• Develop and execute small-molecule purification strategies using preparative SFC and LC, with emphasis on SFC method development and optimization.
• Resolve complex separations by optimizing stationary and mobile phases, selectivity, gradients, sample loading, scale-up, and fraction collection.
• Develop high-throughput compound QC workflows using LC/MS and related analytical techniques to assess identity, purity, and sample quality.
• Collaborate with medicinal chemistry and high-throughput experimentation teams to deliver purified, well-characterized compounds.
• Troubleshoot, maintain, and optimize SFC, LC, and LC/MS platforms, including hardware, software, fluidics, and workflow issues.
• Improve automated purification and QC workflows and evaluate chromatography, automation, informatics, and data-management technologies.

Requirements

• Ph.D. in Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related field with 0–5 years of relevant experience; or an MS with 7+ years or BS with 9+ years of relevant experience.
• Hands-on expertise in small-molecule chromatographic purification and method development.
• Demonstrated expertise in preparative SFC, including method development, optimization, and troubleshooting; preparative LC experience is preferred.
• Strong understanding of chromatographic separation science, medicinal chemistry, and small-molecule drug discovery.
• Strong instrument troubleshooting, scientific problem-solving, communication, and collaboration skills.
• Ability to work on-site at the San Diego Headquarters.

Nice to have

• Experience with high-throughput LC/MS analysis and compound QC.
• Experience with automation, high-throughput workflows, and informatics or data-management systems.
• Experience with Agilent, Shimadzu, or comparable analytical and purification platforms.

Culture & Benefits

• Inclusive environment supporting diversity across backgrounds, cultures, national origins, religions, sexual orientations, and life experiences.
• Company-paid healthcare and flexible spending accounts.
• 401(k) matching and voluntary life insurance.
• Uncapped vacation.
• Work in a new facility with an on-site gym and dining.