2 дня назад
Senior Associate Scientist Purification Process Development (AAV)
75 000 - 108 333$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Senior Associate Scientist Purification Process Development (AAV): Developing and optimizing viral vector purification processes for AAV and non-viral gene therapy manufacturing with an accent on chromatography, filtration, scale-up, and technology transfer. Focus on designing purification studies, troubleshooting process conditions, analyzing data, and implementing robust manufacturing processes with CDMOs and cross-functional teams.
Location: Waltham, Massachusetts, United States; onsite. US and Puerto Rico residents only.
Salary: $75,000–$108,333 per year.
Company
is an R&D-driven biopharmaceutical company developing medicines and vaccines through immunoscience, AI, data, and digital platforms.
What you will do
- Develop, design, and conduct purification experiments for viral vectors, including AAV and non-viral vectors.
- Evaluate new technologies, optimize purification conditions, screen media, and troubleshoot downstream processes.
- Apply chromatography, filtration, UF/DF, virus clearance, and other downstream purification techniques across development scales.
- Support scale-up and implementation of manufacturing processes, including technology transfers with CDMOs.
- Analyze data, prepare technical reports and presentations, and communicate findings with internal and external stakeholders.
- Contribute to scientific manuscripts, patent applications, and a collaborative laboratory culture.
Requirements
- Bachelor’s or master’s degree in chemical engineering, biological or life sciences, or a related field.
- At least 2 years of laboratory or related experience with a bachelor’s degree, or at least 6 months with a master’s degree; academic and research experience is considered.
- Knowledge of purification operations such as depth filtration, AKTA, automated chromatography, tangential flow filtration, UF/DF, and virus clearance or inactivation.
- Understanding of chromatography and separation principles, technical report writing, GLP, and detailed laboratory documentation.
- Ability to learn and perform viral vector analyses using new tools and techniques.
- Ability to work onsite in Waltham, Massachusetts; applicants must be US or Puerto Rico residents.
Nice to have
- Experience with AAV or non-viral vector purification, large-scale manufacturing, or process technology transfer.
- Knowledge of spectrophotometry, ELISA, HPLC, SDS-PAGE, Quality by Design, DOE, and virus clearance studies.
- Experience with gap analyses, risk assessments, Biosafety Level 2 laboratories, and cross-functional collaboration.
- Ability to work under minimal supervision and stand at laboratory equipment for extended periods.
Culture & Benefits
- Supportive, future-focused environment centered on scientific innovation and collaboration.
- Opportunities for career growth through promotion or lateral moves, including international opportunities.
- Company rewards and employee benefit programs.
- Healthcare, prevention and wellness benefits, and at least 14 weeks of gender-neutral parental leave.
- Work at the intersection of biopharma, AI, data, and digital research platforms.
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