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12 дней назад

Scientist Erythroid Biology

Формат работы
onsite
Тип работы
fulltime
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Scientist Erythroid Biology (siRNA/RNA therapeutics): Designing and conducting in vitro and ex vivo assays, developing human primary cell-based systems, and supporting target validation and mechanism-of-action studies with an accent on erythroid biology, hematopoiesis, and multi-color flow cytometry. Focus on optimizing qPCR and RNA-based readouts, collaborating across drug discovery teams, and contributing to IND-enabling studies and data packages.

Location: Thousand Oaks, California, United States

Company

hirify.global is a biotechnology company developing medicines across oncology, inflammation, general medicine, and rare disease.

What you will do

  • Design and execute in vitro and ex vivo assays evaluating siRNA delivery and function.
  • Develop human primary cell-based systems for erythroid biology research.
  • Support target validation and mechanism-of-action studies for siRNA therapeutics.
  • Establish and optimize multi-color flow cytometry panels, qPCR, and RNA-based readouts.
  • Collaborate with Delivery/Chemistry, Translational, and Biomarker teams.
  • Contribute to IND-enabling studies and data packages.

Requirements

  • Doctorate degree; alternatively, a master's degree plus 2 years of scientific experience or a bachelor's degree plus 4 years of scientific experience.
  • Experience with siRNA or RNA therapeutics, including delivery or functional assays.
  • Background in erythroid biology, hematopoiesis, and cell-based functional assays.
  • Strong experience with multi-color flow cytometry and familiarity with gene expression, qPCR, RNA assays, and target engagement assays.
  • Experience working in cross-functional drug discovery teams.

Nice to have

  • Knowledge of hemoglobinopathies, conjugated delivery systems, CRISPR, or gene editing.

Culture & Benefits

  • Employee benefits include medical, dental, vision, life, and disability insurance.
  • Retirement and savings plan with company contributions and flexible spending accounts.
  • Discretionary annual bonus program and stock-based long-term incentives.
  • Paid time-off plans and flexible work models where applicable.
  • Career development opportunities within a collaborative, science-based environment.

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