4 дня назад
Senior Associate Scientist - Process Development (Vaccines)
68 600 - 114 300$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Senior Associate Scientist - Process Development (Vaccines) (Molecular Biology/Cell Culture): Developing robust processes for high-quality protein subunit vaccines with an accent on cell line development, fermentation, and data-driven process optimization. Focus on analyzing relationships between DNA sequence inputs and protein yield and quality, operating cell culture and bioreactor workflows, and communicating experimental conclusions across multidisciplinary teams.
Location: On site in Pearl River, New York, United States. Permanent U.S. work authorization is required; U.S. work visa sponsorship is not available.
Annual base salary: $68,600–$114,300, plus eligibility for a 7.5% bonus target.
Company
develops medicines and vaccines intended to deliver breakthroughs that change patients’ lives.
What you will do
- Optimize cell line development workflows for protein expression, productivity, process efficiency, and biological robustness.
- Execute fermentation experiments and evaluate cell fitness, growth, recovery, protein yield, and purity.
- Analyze experimental data to establish quantitative relationships between DNA sequences and protein yield and quality.
- Collaborate with cell culture, purification, mRNA production, and analytical groups.
- Present experimental data and strategic conclusions in cross-functional meetings.
- Maintain electronic laboratory notebooks and prepare technical, production, and scientific reports.
Requirements
- B.S. degree with 3–5 years of relevant industry or research experience, or an M.S. in bioengineering, biochemistry, chemical engineering, or a related field with 0–3 years of experience.
- Hands-on experience with aseptic cell culture, cell passaging, maintenance, transfection, morphology monitoring, and viability assessment.
- Experience with flow cytometry, cell sorting cytometers, and FlowJo or comparable analysis software.
- Knowledge of DNA/RNA extraction, PCR, ddPCR, RT-PCR, ligation, cloning, transformation, gel electrophoresis, SDS-PAGE, western blot, and ELISA.
- Authorization to work permanently in the United States is required.
Nice to have
- Experience setting up, feeding, sampling, and controlling benchtop or single-use batch and fed-batch bioreactors.
- Hands-on knowledge of NGS sequencing platforms.
Culture & Benefits
- Collaborative, multidisciplinary environment focused on scientific excellence and continuous improvement.
- Work is performed according to scientific, ethical, and regulatory standards.
- Benefits include a 401(k) plan with company contributions, retirement savings contributions, paid vacation, holidays, personal days, caregiver and medical leave, and medical, prescription, dental, and vision coverage.
- Relocation assistance may be available based on business needs and eligibility.
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