1 день назад
Scientist II In Vivo
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Scientist II In Vivo (Biotechnology): Designing, executing, and evaluating in vivo studies for target identification, validation, and drug discovery with an accent on mouse model characterization, efficacy studies, and PK/PD analysis. Focus on complex dosing routes, colony management, tissue processing, regulatory documentation, and collaboration with CROs and academic partners.
Location: Cambridge, UK, at the Babraham Research Campus. Hybrid-friendly work with purposeful in-person collaboration.
Company
is a global biopharmaceutical company developing treatments for serious and rare diseases.
What you will do
- Design, implement, and evaluate in vivo studies conducted internally and through CROs.
- Plan and execute mouse model characterization, efficacy studies, and small-scale PK/PD studies.
- Analyze endpoint data using behavioral and image-based methods and prepare study reports, summaries, and regulatory documents.
- Develop project plans with program leads and senior leadership and coordinate work with vivarium staff, CROs, and academic partners.
- Advise internal stakeholders on study design, data analysis, animal models, methods, and suitable execution locations.
- Lead workflow improvements, implement technology solutions, and mentor colleagues in a matrix-based team.
Requirements
- Current UK Home Office Licence with hands-on in vivo experience is required. Candidates without a current licence or a dormant licence that can be reactivated cannot be employed.
- 4–5 years of relevant experience working with in vivo models and internal or external partners.
- Experience managing colonies, expanding imported or newly generated models, and generating experimental cohorts.
- Experience planning and executing efficacy studies, including complex dosing routes such as IT, ICV, and ICM and cannulation for repeat mouse dosing.
- Experience with mouse model characterization, behavioral phenotyping, image-based analysis, tissue collection, and sample processing.
- Strong analytical, statistical, reporting, and regulatory documentation skills, with a bachelor's degree expected.
Nice to have
- Experience in neurodegenerative, neuroinflammatory, or cardiovascular disease.
- Understanding of genome engineering and transgenic technologies for generating animal models.
- Expertise in CNS tissue collection and processing, including fixation and embedding for histology.
Culture & Benefits
- Flexible work schedules with purposeful in-person collaboration.
- Competitive retirement benefits, global equity awards, and an employee stock purchase plan.
- Career development through internal and external learning programs, LinkedIn Learning, and role-specific training.
- AI-powered and on-demand learning tools and hybrid-friendly technology support.
- Global recognition programs and Employee Resource Groups.
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