4 дня назад
Scientist I or II (In Vivo Drug Discovery)
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Scientist I or II (In Vivo Drug Discovery): Designing, executing, and evaluating in vivo studies for target identification, target validation, and drug discovery programs with an accent on mouse models, efficacy studies, and PK/PD analysis. Focus on selecting and characterizing animal models, coordinating internal and CRO studies, and improving workflows for complex preclinical research.
Location: Babraham Research Campus, Cambridge, UK, with purposeful in-person collaboration
Company
is a global biopharmaceutical company developing treatments for patients with serious and rare diseases.
What you will do
- Design, implement, and evaluate in vivo studies conducted internally and through CROs.
- Plan and execute laboratory studies involving mouse model characterization, behavioral and image-based analysis, efficacy testing, and small-scale PK/PD studies.
- Prepare study reports, summaries, regulatory documents, and electronic database entries.
- Develop in vivo project plans with program leads and senior leadership.
- Coordinate with vivarium staff, CROs, academic partners, and internal stakeholders to deliver study work packages.
- Lead workflow improvements, technology adoption, knowledge capture, and scientific coaching within the matrix-based team.
Requirements
- 4–5 years of relevant experience working with in vivo models and both internal and external partners.
- Current UK Home Office Licence or a dormant UK licence that can be reactivated is required.
- Hands-on experience with animal models, colony management, and generation of experimental cohorts.
- Experience planning and executing efficacy studies, including complex dosing routes such as IT, ICV, and ICM and repeat-dose cannulation in mice.
- Experience with mouse model characterization, behavioral phenotyping, image-based analysis, tissue collection, and sample processing.
- Strong analytical and statistical skills, attention to detail, and experience preparing reports and regulatory documentation.
Nice to have
- Experience in neurodegenerative, neuroinflammatory, or cardiovascular disease research.
- Understanding of genome engineering and transgenic technologies for animal model generation.
- Expertise in CNS tissue collection and histology preparation, including fixation and embedding.
Culture & Benefits
- Work in new laboratories and offices at the Babraham Research Campus.
- Collaborate with biologists, human geneticists, bioinformaticians, data scientists, and computational and synthetic chemists.
- Flexible work schedules with purposeful in-person collaboration and hybrid-friendly technology support.
- Competitive retirement benefits, global equity awards, and Employee Stock Purchase Plan participation.
- Career development through internal and external learning programs, role-specific training, and AI-powered learning tools.
- Global recognition programs and Employee Resource Groups.
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