2 дня назад
Process Development Sr Scientist (Mass Spectrometry)
126 066 - 170 560$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Process Development Sr Scientist (Mass Spectrometry): Developing and applying analytical methods for therapeutic proteins and synthetic molecules with an accent on chromatography, electrophoresis, and LC-MS/MS. Focus on characterizing chemical modifications, generating quality data for drug development and regulatory filings, and advancing complex multidisciplinary studies.
Location: Thousand Oaks, California, United States
Salary: $126,066.05–$170,559.95 per year
Company
is a biotechnology company developing, manufacturing, and delivering medicines for serious illnesses across oncology, inflammation, general medicine, and rare disease.
What you will do
- Define favorable quality characteristics of therapeutic proteins and synthetic molecules.
- Develop and apply sample preparation and analytical methods using chromatography, electrophoresis, and mass spectrometry.
- Characterize quality attributes and chemical modifications including glycosylation, oxidation, deamidation, aspartate isomerization, and hydroxylation.
- Generate accurate, high-quality data for drug development and regulatory filings while maintaining electronic laboratory records.
- Collaborate with multidisciplinary scientists and independently advance projects within deadlines.
- Contribute to patents, publications, technology programs, and drug development initiatives.
Requirements
- Doctorate degree, or a master’s degree with 2 years of scientific experience, or a bachelor’s degree with 4 years of scientific experience.
- Ph.D. in analytical chemistry or biochemistry with emphasis on mass spectrometry, chromatography, electrophoresis, or another analytical technique.
- Experience with peptide mapping and intact and reduced LC-MS analysis of chemical modifications.
- Experience operating Thermo Q-Exactive and Agilent mass spectrometers, Agilent and Waters HPLC/UHPLC systems, and related data-processing software.
- Knowledge of statistical data processing using Excel, Spotfire, and JMP.
- Strong scientific communication, complex problem-solving, planning, independent execution, collaboration, mentorship, and leadership skills.
Nice to have
- Two or more years of post-Ph.D. experience in pharmaceutical or biotechnology process and product development.
- Programming experience with R, Python, C++, or machine learning languages.
- Experience with automation, robotics, or liquid handlers.
Culture & Benefits
- Collaborative, innovative, and science-based work environment.
- Health, dental, vision, life, disability, and flexible spending benefits.
- Retirement and savings plan with company contributions.
- Annual bonus program and stock-based long-term incentives.
- Paid time off and career development opportunities.
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