9 дней назад
Lead Scientist/Associate Director (Cancer Biology)
100 000 - 186 300$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Lead Scientist/Associate Director (Cancer Biology) (Patient-Derived Models): Managing and advancing patient-derived model systems, including organoids, PDXs, and patient-derived cell lines, with an accent on functional precision oncology, biomarker discovery, and multi-omics integration. Focus on leading model repository operations, designing drug sensitivity and mechanism-of-action studies, developing bioinformatics and AI/ML approaches, and coordinating translational research collaborations.
Location: Boston, Massachusetts, United States; 100% onsite
Salary: $100,000–$186,300 per year
Company
is a cancer research and patient care institute focused on translational oncology, education, and improving patient outcomes.
What you will do
- Oversee the establishment, maintenance, expansion, validation, and quality control of a repository of patient-derived models and biospecimens.
- Design and execute studies supporting biomarker discovery, drug sensitivity testing, and mechanism-of-action investigations.
- Integrate multi-omics data, including single-cell RNA sequencing and proteomics, with functional assays.
- Co-direct CPDM operations, mentor junior scientists and research associates, and contribute to strategic planning and resource allocation.
- Coordinate internal, academic, and industry collaborations, including IND-enabling studies, assay validation, and large-scale biospecimen handling.
- Develop and apply bioinformatics and AI/ML approaches to analyze complex datasets and advance functional precision medicine platforms.
Requirements
- Ph.D. in Biochemistry, Biomedical Sciences, Cancer Biology, or a closely related field.
- 5+ years of postdoctoral or industry experience with patient-derived models or functional precision medicine assays.
- Experience managing large model repositories, model validation, and multi-omics workflows.
- Strong publication record in translational oncology or a related field.
- Expertise in 3D cell culture, organoid techniques, PDX models, high-throughput drug screening, molecular biology, immunohistochemistry, flow cytometry, multiplex imaging, and bioinformatics using R/Linux.
- Proven ability to lead teams, manage projects, and collaborate across disciplines in a translational research environment.
Nice to have
- Experience in cancer biology, AI-enabled translational science, companion diagnostics, or functional precision medicine platforms.
- Experience with lab automation, digitization, and ELN/LIMS implementation.
- Successful grant funding and industry or academic partnerships.
- Experience in a CLIA/CAP environment.
Culture & Benefits
- Access to state-of-the-art facilities and large biospecimen collections.
- Collaboration with academic and industry key opinion leaders.
- Competitive salary, comprehensive benefits, and professional development opportunities.
- Supportive, mission-driven environment focused on innovative cancer research and patient outcomes.
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