2 дня назад
Senior Scientist (Proteomics)
127 122 - 171 988$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Scientist (Proteomics): Developing and implementing high-throughput mass spectrometry-based proteomics workflows and screening platforms for target identification and drug discovery with an accent on automated sample preparation, LC-MS/MS analysis, and proteomics data interpretation. Focus on optimizing next-generation screening workflows, troubleshooting high-throughput mass spectrometry systems, and generating insights into mechanism of action, target engagement, and selectivity.
Location: US - California - Thousand Oaks
Salary: $127,121.75–$171,988.25 annually
Company
is a biotechnology company developing medicines across oncology, inflammation, general medicine, and rare disease.
What you will do
- Design, develop, and optimize high-throughput mass spectrometry-based proteomics workflows and screening platforms for drug discovery.
- Execute automated sample preparation and LC-MS/MS analyses across multiple high-throughput proteomics assays.
- Operate and troubleshoot high-throughput mass spectrometry systems and advance screening platform technologies.
- Collaborate with chemistry, biology, and disease area teams as a technical and scientific subject matter expert.
- Analyze high-dimensional proteomics data to generate insights into mechanism of action, target engagement, and selectivity.
- Present findings and maintain accurate documentation of experiments, protocols, and analyses.
Requirements
- PhD, PharmD, or MD with relevant experience; or a master’s degree with 4 years of directly related experience; or a bachelor’s degree with 6 years of directly related experience.
- Experience developing mass spectrometry-based proteomics assays and analyzing proteomics data.
- Hands-on experience operating advanced mass spectrometry platforms, such as Orbitrap Astral.
- Experience with sample preparation miniaturization and automation platforms.
- Strong quantitative, computational, organizational, verbal, and written communication skills.
- Ability to produce reliable and reproducible results in a highly integrated, collaborative environment.
Nice to have
- Doctorate in proteomics, chemoproteomics, biochemistry, chemistry, or a related discipline.
- 3+ years of experience in the biotechnology or pharmaceutical industry.
- Experience with targeted protein degradation or E3 ligase biology.
Culture & Benefits
- Collaborative, innovative, and science-based work environment.
- Health, dental, vision, life, and disability insurance.
- Retirement and savings plan with company contributions and flexible spending accounts.
- Discretionary annual bonus program and stock-based long-term incentives.
- Award-winning time-off plans and career development opportunities.
- Flexible work models where applicable.
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